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RMI1 RMI1 MUS81 MUS81 AT1G20750 AT1G20750 AT2G18150 AT2G18150 RECQ4A RECQ4A RPA70C RPA70C RAD51B RAD51B AT1G08390 AT1G08390 RPA1A RPA1A RPA70B RPA70B AT2G01440 AT2G01440
"AT1G08390" - Uncharacterized protein in Arabidopsis thaliana
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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Gene Fusion
Cooccurence
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Databases
Textmining
[Homology]
Score
AT1G08390Uncharacterized protein (137 aa)    
Predicted Functional Partners:
AT1G20750
RAD3-like DNA-binding helicase protein (1144 aa)
           
  0.987
AT2G01440
ATP-dependent DNA helicase RecG; Critical role in recombination and DNA repair (973 aa)
           
  0.810
RMI1
Uncharacterized protein (677 aa)
           
  0.780
RPA1A
Replication factor A1; Component of the replication protein A complex (RPA) required for DNA recombination, repair and replication. The activity of RPA is mediated by single-stranded DNA binding and protein interactions. Plays an essential role at later stages of meiotic recombination events required for the formation of class I crossovers. Is essential for normal progression through meiosis in pollen mother cells. Is involved in repair of double-strand DNA breaks (DSBs) induced by genotoxic stresses, but does not seem to be required for the repair of meiotic DSBs (640 aa)
           
  0.739
RPA70B
RPA70-kDa subunit B; Component of the replication protein A complex (RPA) required for DNA recombination, repair and replication. The activity of RPA is mediated by single-stranded DNA binding and protein interactions (By similarity). Probably involved in repair of double-strand DNA breaks (DSBs) induced by genotoxic stresses (By similarity) (604 aa)
           
  0.737
RPA70C
Replication factor-A protein 1-related; Component of the replication protein A complex (RPA) required for DNA recombination, repair and replication. The activity of RPA is mediated by single-stranded DNA binding and protein interactions. Probably involved in repair of double-strand DNA breaks (DSBs) induced by genotoxic stresses (By similarity) (853 aa)
           
  0.679
RAD51B
DNA repair protein RAD51-like 2; May be involved in the homologous recombination repair (HRR) pathway of double-stranded DNA breaks arising during DNA replication or induced by DNA-damaging agents (371 aa)
           
  0.670
MUS81
MMS AND UV SENSITIVE 81; Interacts with EME1 to form a DNA structure-specific endonuclease with substrate preference for branched DNA structures with a 5’-end at the branch nick. Typical substrates include 3’- flap structures, D-loops, replication forks, nicked Holliday junctions and also intact Holliday junctions with a reduced efficiency. May be required in mitosis for the processing of stalled or collapsed replication fork intermediates. Plays a role in DNA repair and in genotoxic stress-induced homologous recombination (HR) in somatic cells. Mediates a subset of meiotic recombinati [...] (659 aa)
           
  0.635
RECQ4A
ATP-dependent DNA helicase Q-like 4A; 3’-5’ DNA helicase that may play a role in the repair of DNA. Required for maintenance of genome stability by modulation of the DNA damage response and repression of crossovers. Confers resistance to genotoxic stress (1188 aa)
           
  0.604
AT2G18150
Peroxidase 15; Removal of H(2)O(2), oxidation of toxic reductants, biosynthesis and degradation of lignin, suberization, auxin catabolism, response to environmental stresses such as wounding, pathogen attack and oxidative stress. These functions might be dependent on each isozyme/isoform in each plant tissue (338 aa)
           
  0.491
Your Current Organism:
Arabidopsis thaliana
NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress
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