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RAC2 RAC2 ARAC5 ARAC5 RAC10 RAC10 GDI GDI RAC3 RAC3 RAC6 RAC6 ROP1 ROP1 AT1G12070 AT1G12070 ROP2 ROP2 ARAC9 ARAC9 ARAC1 ARAC1
"AT1G12070" - Immunoglobulin E-set superfamily protein in Arabidopsis thaliana
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AT1G12070Immunoglobulin E-set superfamily protein (223 aa)    
Predicted Functional Partners:
ARAC5
RAC-like GTP binding protein 5; May be involved in cell polarity control during the actin-dependent tip growth of root hairs (196 aa)
     
  0.998
ROP2
RHO-related protein from plants 2; Inactive GDP-bound Rho GTPases reside in the cytosol, are found in a complex with Rho GDP-dissociation inhibitors (Rho GDIs), and are released from the GDI protein in order to translocate to membranes upon activation (By similarity). May be involved in cell polarity control during the actin-dependent tip growth of root hairs. May regulate a WAVE complex that activates the Arp2/3 complex (195 aa)
     
  0.997
RAC3
RAC-like 3; Inactive GDP-bound Rho GTPases reside in the cytosol, are found in a complex with Rho GDP-dissociation inhibitors (Rho GDIs), and are released from the GDI protein in order to translocate to membranes upon activation. May be involved in cell polarity control during the actin-dependent tip growth of root hairs (PubMed-11387211). SPK1-dependent activation is required for auxin-mediated inhibition of PIN2 internalization during gravitropic responses (PubMed-22683260) (198 aa)
     
  0.997
ROP1
RHO-related protein from plants 1; May be involved in cell polarity control during the actin-dependent tip growth of pollen tubes. May regulate callose synthase 1 (CALS1) activity through the interaction with UGT1 (197 aa)
     
  0.996
ARAC9
Arabidopsis RAC-like 9; Inactive GDP-bound Rho GTPases reside in the cytosol, are found in a complex with Rho GDP-dissociation inhibitors (Rho GDIs), and are released from the GDI protein in order to translocate to membranes upon activation (209 aa)
     
  0.995
RAC2
RAC-like 2; Inactive GDP-bound Rho GTPases reside in the cytosol, are found in a complex with Rho GDP-dissociation inhibitors (Rho GDIs), and are released from the GDI protein in order to translocate to membranes upon activation (201 aa)
     
  0.995
ARAC1
Arabidopsis RAC-like 1; Inactive GDP-bound Rho GTPases reside in the cytosol, are found in a complex with Rho GDP-dissociation inhibitors (Rho GDIs), and are released from the GDI protein in order to translocate to membranes upon activation (197 aa)
     
  0.994
RAC6
RAC-like 6; May be involved in cell polarity control during the actin-dependent tip growth of pollen tubes (197 aa)
     
  0.993
GDI
RAB GDP-dissociation inhibitor; Regulates the GDP/GTP exchange reaction of most RAB proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP (445 aa)
     
  0.982
RAC10
RAC-like 10; Involved in local disassembly of cortical microtubules when associated with ICR5 (215 aa)
     
  0.963
Your Current Organism:
Arabidopsis thaliana
NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress
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