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SDE3 SDE3 RRP4 RRP4 AT1G12830 AT1G12830 AT5G38720 AT5G38720 AT3G18790 AT3G18790 AT5G55660 AT5G55660
"AT1G12830" - Uncharacterized protein in Arabidopsis thaliana
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AT1G12830Uncharacterized protein (213 aa)    
Predicted Functional Partners:
AT3G18790
pre-mRNA-splicing factor ISY1 (300 aa)
     
        0.435
RRP4
Ribosomal RNA processing 4; Non-catalytic component of the RNA exosome complex which has 3’->5’ exoribonuclease activity and participates in a multitude of cellular RNA processing, maturation and degradation events. In vitro, is an active and distributive 3’->5’ exonuclease requiring a free 3’-OH on the substrate and releasing nucleoside 5’-monophosphates (PubMed-11809881). Required for normal embryo development (PubMed-18160042) (322 aa)
     
        0.431
AT5G55660
DEK domain-containing chromatin associated protein (778 aa)
     
        0.422
AT5G38720
Uncharacterized protein (306 aa)
     
        0.416
SDE3
SILENCING DEFECTIVE; Probable RNA helicase required for post-transcriptional gene silencing (PTGS), a process that provides protection in plants against virus infection and can suppress expression of transgenes. Plays a central role in RNA interference (RNAi) process, a process that mediates mRNA destruction of translational repression. Required for the assembly of the RISC complex, a complex required for target RNA destruction or repression. May be required in the RISC assembly to unwind miRNAs, in the production of single-stranded miRNA from the double-stranded miRNA, a key step in R [...] (1002 aa)
     
        0.410
Your Current Organism:
Arabidopsis thaliana
NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress
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