Full Link:
STRINGSTRING
CHX23 CHX23 KEA6 KEA6 KEA1 KEA1 KEA3 KEA3 HKT1 HKT1 CHX17 CHX17 NHX8 NHX8 KEA4 KEA4 KEA2 KEA2 SOS3 SOS3 CHX15 CHX15
"NHX8" - Na+/H+ exchanger 8 in Arabidopsis thaliana
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NHX8Na+/H+ exchanger 8; May act in low affinity electroneutral exchange of protons for cations such as Na(+) or K(+) across membranes. May also exchange Li(+) and Cs(+) with a lower affinity (By similarity) (756 aa)    
Predicted Functional Partners:
KEA1
K+ efflux antiporter 1; K(+)/H(+) antiporter involved in K(+) homeostasis and osmotic adjustment (1193 aa)
     
 
  0.916
KEA3
K+ efflux antiporter 3; Electroneutral K(+)/H(+) antiporter. Accelerates photosynthetic acclimation in fluctuating light environments (776 aa)
     
 
  0.871
CHX23
cation/H+ exchanger 23; Operates as a K(+)/H(+) antiporter or Na(+)/H(+) antiporter of the chloroplast envelope that functions in pH homeostasis and chloroplast development. Monovalent cation transporter with a preference for Cs(+), K(+) and Rb(+) relative to Na(+) or Li(+). Required for pollen tube guidance, but not for normal pollen development. May also be involved in the development or function of the female gametophyte (867 aa)
     
 
  0.832
CHX17
cation/H+ exchanger 17; Operates as a K(+)/H(+) antiporter that controls K(+) acquisition and homeostasis (820 aa)
     
 
  0.831
KEA6
K+ efflux antiporter 6; K(+)/H(+) antiporter involved in K(+) homeostasis and osmotic adjustment (597 aa)
   
 
  0.820
SOS3
SALT OVERLY SENSITIVE 3; Acts as a calcium sensor involved in the regulatory pathway for the control of intracellular Na(+) and K(+) homeostasis and salt tolerance. Binding of a CBL protein to the regulatory NAF domain of a CIPK serine-threonine protein kinase lead to the activation of the kinase in a calcium-dependent manner. Operates in synergy with CIPK24/SOS2 to activate the plasma membrane Na(+)/H(+) antiporter SOS1. Involved in salt stress responses by mediating calcium-dependent microfilament reorganization. The CBL4/CIPK6 complex mediates translocation of AKT2 from the endoplas [...] (222 aa)
       
 
  0.780
KEA2
K+ efflux antiporter 2; Electroneutral K(+)/H(+) antiporter modulating monovalent cation and pH homeostasis in plastids (PubMed-22551943, PubMed-24278440). Transports K(+) and Cs(+) preferentially relative to Na(+) or Li(+) (PubMed-22551943). May function in osmotic adjustment (PubMed-24278440) (1185 aa)
     
 
  0.778
KEA4
K+ efflux antiporter 4; K(+)/H(+) antiporter involved in K(+) homeostasis and osmotic adjustment (592 aa)
     
 
  0.770
HKT1
Sodium transporter HKT1; Sodium transporter protein, which plays a central role in plant tolerance to salt. Upon prolongated exposure to high concentrations, Na(+) translocates from the roots to the transpiring leaves where it can increase to toxic level. Involved in Na(+) recirculation from shoots to roots, probably by mediating Na(+) loading into the phloem sap in shoots and unloading in roots, thereby removing large amounts of Na(+) from the shoot. Does not transport K(+) but regulates K(+) nutrient status via its ability to facilitate Na(+) homeostasis. Probably not involved in roo [...] (506 aa)
     
 
  0.766
CHX15
cation/H(+) antiporter 15; May operate as a cation/H(+) antiporter (821 aa)
     
 
  0.729
Your Current Organism:
Arabidopsis thaliana
NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress
Server load: low (1%)