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RAC10 RAC10 SEC3A SEC3A RIC4 RIC4 ROP1 ROP1 RAC3 RAC3 AT4G24840 AT4G24840 ROP2 ROP2 ICR1 ICR1 ARAC5 ARAC5 RIC1 RIC1 AT3G11460 AT3G11460
"ICR1" - Interactor of constitutive active ROPs 1 in Arabidopsis thaliana
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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[Homology]
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ICR1Interactor of constitutive active ROPs 1; Acts as a scaffold, mediating interaction of ROPs with different proteins. Required for primary and adventitious root maintenance, but not for their formation. Promotes the stabilization of ARAC11 on the plasma membrane of the pollen tube initiation site but not the activation of ARAC11. Regulates directionality of polar auxin transport, and is required for the formation of a stable auxin maximum and tip localized auxin gradient during embryogenesis, organogenesis, and meristem activity. Involved in exocytosis and in the recycling of PIN protei [...] (344 aa)    
Predicted Functional Partners:
ROP1
RHO-related protein from plants 1; May be involved in cell polarity control during the actin-dependent tip growth of pollen tubes. May regulate callose synthase 1 (CALS1) activity through the interaction with UGT1 (197 aa)
       
 
  0.920
SEC3A
Exocyst complex component sec3A; Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane during regulated or polarized secretion. Involved in polarized cell growth and organ morphogenesis. During cytokinesis, involved in cell plate initiation, cell plate maturation and formation of new primary cell wall. During cytokinesis, involved in cell plate initiation, cell plate maturation and formation of new primary cell wall (888 aa)
       
 
  0.870
RIC4
ROP-interactive CRIB motif-containing protein 4; Functions as downstream effector of Rho-related GTP binding proteins of the "Rho of Plants" (ROPs) family. Participates in the propagation of ROP GTPase signals in specific cellular responses. Required for actin cortical microfilament assembly. Activated by ARAC4/ROP2 to promote the assembly of cortical actin microfilaments required for lobe formation and lateral expansion of pavement cells. Interaction with, and activation by ARAC4/ROP2 is inhibited by RIC1. Functions as downstream effector of ARAC11/ROP1 to promote the assembly of apic [...] (153 aa)
           
  0.841
RAC3
RAC-like 3; Inactive GDP-bound Rho GTPases reside in the cytosol, are found in a complex with Rho GDP-dissociation inhibitors (Rho GDIs), and are released from the GDI protein in order to translocate to membranes upon activation. May be involved in cell polarity control during the actin-dependent tip growth of root hairs (PubMed-11387211). SPK1-dependent activation is required for auxin-mediated inhibition of PIN2 internalization during gravitropic responses (PubMed-22683260) (198 aa)
           
  0.801
AT4G24840
Uncharacterized protein (756 aa)
       
      0.746
AT3G11460
Pentatricopeptide repeat-containing protein (623 aa)
       
      0.746
ROP2
RHO-related protein from plants 2; Inactive GDP-bound Rho GTPases reside in the cytosol, are found in a complex with Rho GDP-dissociation inhibitors (Rho GDIs), and are released from the GDI protein in order to translocate to membranes upon activation (By similarity). May be involved in cell polarity control during the actin-dependent tip growth of root hairs. May regulate a WAVE complex that activates the Arp2/3 complex (195 aa)
           
  0.732
ARAC5
RAC-like GTP binding protein 5; May be involved in cell polarity control during the actin-dependent tip growth of root hairs (196 aa)
           
  0.709
RIC1
ROP-interactive CRIB motif-containing protein 1; Functions as downstream effector of Rho-related GTP binding proteins of the "Rho of Plants" (ROPs) family. Participates in the propagation of ROP GTPase signals in specific cellular responses. Required for cortical microtubule organization. Promotes microtubule bundling and formation of well- ordered microtubule arrays in the neck region of pavement cells. This restricts cell lateral expansion to generate the narrow neck morphology of pavement cells. Its function is inhibited when it interacts with activated ARAC4/ROP2. Represses ARAC4/R [...] (224 aa)
       
 
  0.707
RAC10
RAC-like 10; Involved in local disassembly of cortical microtubules when associated with ICR5 (215 aa)
           
  0.680
Your Current Organism:
Arabidopsis thaliana
NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress
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