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TAF7 TAF7 SET27 SET27 SDG16 SDG16 TOPII TOPII SIZ1 SIZ1 SDG14 SDG14 AT1G17790 AT1G17790 SDG29 SDG29 ATX2 ATX2 ADA2A ADA2A AT2G47210 AT2G47210
"AT1G17790" - DNA-binding bromodomain-containing protein in Arabidopsis thaliana
Nodes:
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Cooccurence
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[Homology]
Score
AT1G17790DNA-binding bromodomain-containing protein (487 aa)    
Predicted Functional Partners:
AT2G47210
DNA methyltransferase 1-associated protein 1; Component of the SWR1 complex which mediates the ATP- dependent exchange of histone H2A for the H2A variant HZT1 leading to transcriptional regulation of selected genes by chromatin remodeling. Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of selected genes principally by acetylation of nucleosomal histone H4 and H2A (441 aa)
     
 
  0.896
TOPII
Topoisomerase II; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double-strand breaks (1473 aa)
     
  0.819
TAF7
TBP-associated factor 7; TAFs are components of the transcription factor IID (TFIID) complex that is essential for mediating regulation of RNA polymerase transcription (239 aa)
     
 
  0.811
SDG16
SET domain protein 16; Histone methyltransferase (1027 aa)
     
 
  0.799
SDG14
SET domain protein 14; Histone methyltransferase (1018 aa)
     
 
  0.798
SDG29
SET domain group 29; Histone methyltransferase (1043 aa)
     
 
  0.798
SET27
Homologue of trithorax; Histone methyltransferase. Methylates ’Lys-4’ of histone H3. H3 ’Lys-4’ methylation represents a specific tag for epigenetic transcriptional activation. Required to maintain the active state of class A (AP1 and AP2), class B (PI and AP3) and class C (AG) floral homeotic genes at early stages of flower development. Regulates floral organ identity and flowering transition. Functions as a receptor for the lipid messenger phosphatidylinositol 5-phosphate (PI5P), which regulates negatively its transcriptional activation activity (1062 aa)
     
 
  0.782
SIZ1
E3 SUMO-protein ligase SIZ1; E3 SUMO protein ligase involved in regulation processes. Mediates SUMO/ attachment to PHR1, a MYB transcriptional activator controlling the phosphate deficiency responses. Functions as an upstream negative regulator of salicylic acid (SA) accumulation and subsequent SA-mediated systemic acquired resistance (SAR) signaling. Probably not involved in jasmonic acid (JA)-mediated defense response. Participates in abiotic stress-induced sumoylation. Controls heat shock-induced SUMO1 and SUMO2 conjugation and facilitates basal thermotolerance. Involved in freezing [...] (885 aa)
     
 
  0.777
ATX2
Trithorax-like protein 2; Histone methyltransferase (1083 aa)
     
 
  0.759
ADA2A
Homolog of yeast ADA2 2A; Required for the function of some acidic activation domains, which activate transcription from a distant site. The exact mechanism of action is not yet known (By similarity). ADA2 stimulates the acetyltransferase activity of GCN5 on free histones or nucleosomes, probably by opening up the promoter region (555 aa)
     
 
  0.748
Your Current Organism:
Arabidopsis thaliana
NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress
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