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AT1G30350 AT1G30350 CPSF160 CPSF160 nPAP nPAP PAPS1 PAPS1 FY FY FIP1[V] FIP1[V] CPSF100 CPSF100 CSTF77 CSTF77 CSTF64 CSTF64 CPSF73-I CPSF73-I CPSF30 CPSF30
"PAPS1" - poly(A) polymerase 1 in Arabidopsis thaliana
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
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Known Interactions
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experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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PAPS1poly(A) polymerase 1; Essential protein (PubMed-19956626). Polymerase that creates the 3’-poly(A) tail of mRNA’s (PubMed-15297145). Also required for the endoribonucleolytic cleavage reaction at some polyadenylation sites. May acquire specificity through interaction with a cleavage and polyadenylation specificity factor (CPSF) at its C-terminus (By similarity) (713 aa)    
Predicted Functional Partners:
nPAP
Nuclear poly(a) polymerase; Essential protein (PubMed-19956626). Polymerase that creates the 3’-poly(A) tail of mRNA’s (PubMed-15297145). Also required for the endoribonucleolytic cleavage reaction at some polyadenylation sites. May acquire specificity through interaction with a cleavage and polyadenylation specificity factor (CPSF) at its C-terminus (By similarity) (765 aa)
       
 
0.996
CSTF77
Tetratricopeptide repeat-containing protein; One of the multiple factors required for polyadenylation and 3’-end cleavage of pre-mRNAs (By similarity). Required for the targeted 3’ processing of antisense transcripts that triggers transcriptional silencing of the corresponding sense gene (PubMed-19965720) (734 aa)
     
  0.987
FIP1[V]
FIP1 [V]-like protein; Essential gene (PubMed-16282318). Component of the cleavage and polyadenylation specificity factor (CPSF) complex that plays a key role in pre-mRNA 3’-end formation, recognizing the AAUAAA signal sequence and interacting with poly(A) polymerase and other factors to bring about cleavage and poly(A) addition. FIP1L1 contributes to poly(A) site recognition and stimulates poly(A) addition. Binds to U-rich RNA sequence elements surrounding the poly(A) site. May act to tether poly(A) polymerase to the CPSF complex (By similarity) (1196 aa)
     
 
  0.986
CPSF160
Cleavage and polyadenylation specificity factor 160; CPSF plays a key role in pre-mRNA 3’-end formation, recognizing the AAUAAA signal sequence and interacting with poly(A)polymerase and other factors to bring about cleavage and poly(A) addition. This subunit is involved in the RNA recognition step of the polyadenylation reaction (1442 aa)
     
  0.985
CPSF73-I
Cleavage and polyadenylation specificity factor 73-I; Component of the cleavage and polyadenylation specificity factor (CPSF) complex that play a key role in pre-mRNA 3’-end formation, recognizing the AAUAAA signal sequence and interacting with poly(A) polymerase and other factors to bring about cleavage and poly(A) addition. May function as mRNA 3’-end- processing endonuclease and also be involved in the histone 3’-end pre-mRNA processing (693 aa)
     
  0.980
CSTF64
Cleavage stimulating factor 64; One of the multiple factors required for polyadenylation and 3’-end cleavage of pre-mRNAs (By similarity). This subunit is directly involved in the binding to pre-mRNAs, especially on the 3’ non-coding region (PubMed-12379796). Required for the targeted 3’ processing of antisense transcripts that triggers transcriptional silencing of the corresponding sense gene (PubMed-17008405, PubMed-19965720) (461 aa)
     
  0.973
AT1G30350
Pectate lyase (368 aa)
           
  0.956
CPSF30
Cleavage and polyadenylation specificity factor 30; Component of the cleavage and polyadenylation specificity factor (CPSF) complex that play a key role in pre-mRNA 3’-end formation. May interact with poly(A) polymerase and other factors to bring about cleavage and poly(A) addition (By similarity). Mediates poly(A) site selection (PubMed-23136375). Binds RNA in a calcium-dependent manner (PubMed-16500995, PubMed-17576667, PubMed-20214900). Exhibits endonuclease activity with an ability to nick and degrade linear as well as circular single-stranded RNA that leaves RNA 3’ ends with hydro [...] (631 aa)
     
  0.947
FY
Flowering time control protein FY; Plays a role in the regulation of flowering time in the autonomous flowering pathway by decreasing FLOWERING LOCUS C mRNA levels. Required for the negative autoregulation of FCA expression. Acts probably as an RNA 3’ end-processing factor. Required for growth and development in plants (653 aa)
     
 
  0.944
CPSF100
Cleavage and polyadenylation specificity factor 100; CPSF plays a key role in pre-mRNA 3’-end formation, recognizing the AAUAAA signal sequence and interacting with poly(A)polymerase and other factors to bring about cleavage and poly(A) addition (By similarity). Required for antisense-RNA- mediated gene silencing (PubMed-17008405) (739 aa)
     
  0.939
Your Current Organism:
Arabidopsis thaliana
NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress
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