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HMA6 HMA6 RAN1 RAN1 HMA4 HMA4 HMA1 HMA1 AT5G22460 AT5G22460 HMA5 HMA5 sks7 sks7 HMA3 HMA3 HMA8 HMA8 HMA2 HMA2 PPC2 PPC2
"sks7" - SKU5 similar 7 in Arabidopsis thaliana
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
sks7SKU5 similar 7 (538 aa)    
Predicted Functional Partners:
AT5G22460
alpha/beta-Hydrolases superfamily protein (340 aa)
           
  0.960
PPC2
Phosphoenolpyruvate carboxylase 2; Through the carboxylation of phosphoenolpyruvate (PEP) it forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle (963 aa)
           
  0.741
HMA3
Heavy metal atpase 3 (542 aa)
   
 
  0.727
HMA4
Heavy metal atpase 4; Involved in cadmium/zinc transport (1172 aa)
   
 
  0.724
RAN1
RESPONSIVE-TO-ANTAGONIST 1; Involved in copper import into the cell. Essential for ethylene signaling, which requires copper. Acts by delivering copper to create functional hormone receptors (1001 aa)
   
 
  0.717
HMA8
P-type ATPase; Mediates copper transfer across the chloroplast thylakoid membrane. Required for copper delivery into the thylakoids lumen, which is essential for the function of copper proteins (883 aa)
   
 
  0.717
HMA1
Heavy metal atpase 1; Involved in cadmium/zinc transport (819 aa)
   
 
  0.717
HMA6
P-type ATP-ase 1; Mediates copper transfer across the plastid envelope. Required for the delivery of copper into the plastid stroma, which is essential for the function of copper proteins. Seems to be selective for monovalent copper Cu(+) transport. Plays also a role in glucose signaling-mediated cell proliferation of root meristem in non-green tissues (949 aa)
   
 
  0.717
HMA2
Heavy metal atpase 2; Plays an important role in zinc transport and homeostasis. Could also be involved in cadmium detoxification (951 aa)
   
 
  0.717
HMA5
Heavy metal atpase 5; Involved in copper import into the cell. May play a role in copper detoxification in roots (995 aa)
   
 
  0.717
Your Current Organism:
Arabidopsis thaliana
NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress
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