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AHBP-1B AHBP-1B TGA6 TGA6 CXIP1 CXIP1 NPR1 NPR1 GRX480 GRX480 NTRC NTRC WRKY40 WRKY40 NTRB NTRB TRX5 TRX5 NTRA NTRA GRXS17 GRXS17
"GRX480" - glutaredoxin-C9 in Arabidopsis thaliana
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
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experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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[Homology]
Score
GRX480glutaredoxin-C9; Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins (By similarity) (137 aa)    
Predicted Functional Partners:
NTRC
NADPH-dependent thioredoxin reductase 3; Thioredoxin reductase (TR) that exhibits both TR and thioredoxin (Trx) activities. Contains a C-terminal functional Trx domain. Functions as an electron donor for plastidial 2-Cys peroxiredoxins and participates in a NADPH-dependent hydrogen peroxide scavenging system in chloroplasts in the dark. Required for chlorophyll biosynthesis and biogenesis of the photosynthetic apparatus. Activates aerobic cyclase which converts Mg- protoporhyrin monomethyl ester into protochlorophyllide. Involved in a light-dependent regulation of starch biosynthesis b [...] (529 aa)
   
 
  0.895
AHBP-1B
Transcription factor TGA2; Transcriptional activator that binds specifically to the DNA sequence 5’-TGACG-3’. Recognizes ocs elements like the as-1 motif of the cauliflower mosaic virus 35S promoter. Binding to the as-1-like cis elements mediate auxin- and salicylic acid-inducible transcription. Required to induce the systemic acquired resistance (SAR) via the regulation of pathogenesis-related genes expression. Binding to the as-1 element of PR-1 promoter is salicylic acid- inducible and mediated by NPR1. Could also bind to the C-boxes (5’-ATGACGTCAT-3’) with high affinity (330 aa)
       
 
  0.887
TRX5
Thioredoxin H5; Thiol-disulfide oxidoreductase involved in response to pathogens and oxidative stresses. Required for the response to victorin, a phytotoxin which induces programmed cell death in sensitive plants. Possesses insulin disulfide bonds reducing activity (118 aa)
   
 
  0.837
NPR1
Regulatory protein NPR1; May act as a substrate-specific adapter of an E3 ubiquitin-protein ligase complex (CUL3-RBX1-BTB) which mediates the ubiquitination and subsequent proteasomal degradation of target proteins (By similarity). Key positive regulator of the SA- dependent signaling pathway that negatively regulates JA-dependent signaling pathway. Mediates the binding of TGA factors to the as-1 motif found in the pathogenesis-related PR-1 gene, leading to the transcriptional regulation of the gene defense. Controls the onset of systemic acquired resistance (SAR). Upon SAR induction, [...] (593 aa)
       
 
  0.822
TGA6
Transcription factor TGA6 (355 aa)
       
 
  0.781
GRXS17
Monothiol glutaredoxin 17; May only reduce GSH-thiol disulfides, but not protein disulfides (Probable). Participates probably to the maturation of iron-sulfur proteins and to the regulation of the redox state of the BOLA proteins. The GRXS17-BOLA2 heterodimer binds a labile, oxygen sensitive iron-sulfur cluster (PubMed-24714563) (488 aa)
   
 
  0.767
WRKY40
WRKY DNA-binding protein 40; Transcription factor. Interacts specifically with the W box (5’-(T)TGAC[CT]-3’), a frequently occurring elicitor- responsive cis-acting element (By similarity) (302 aa)
     
   
  0.718
CXIP1
CAX interacting protein 1; May only reduce GSH-thiol disulfides, but not protein disulfides (Potential). Probably involved in the regulation of the redox state of the BOLA proteins (Potential). May act as Fe-S cluster donors to Fe-S cluster-requiring proteins (PubMed-18044966). May protect cells against protein oxidative damage (PubMed-16829529). May regulate CAX cation transporters (PubMed-16829529). The GRXS14-BOLA1 heterodimer binds a labile, oxygen sensitive Fe-S cluster (PubMed-24714563) (173 aa)
   
 
  0.711
NTRB
Thioredoxin reductase 1; Possesses thioredoxin-disulfide reductase activity towards thioredoxins O1, O2 and F3 (375 aa)
   
 
  0.695
NTRA
NADPH-dependent thioredoxin reductase A; Possesses thioredoxin-disulfide reductase activity towards thioredoxins O1, O2 and F3 (378 aa)
   
 
  0.694
Your Current Organism:
Arabidopsis thaliana
NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress
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