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RSW4 RSW4 AT4G24300 AT4G24300 BES1 BES1 AT1G63210 AT1G63210 IWS1 IWS1 SPT16 SPT16 RPOB RPOB NRPB2 NRPB2 GTC2 GTC2 GTB1 GTB1 ELF8 ELF8
"IWS1" - Transcription elongation factor in Arabidopsis thaliana
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
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some 3D structure is known or predicted
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Predicted Interactions
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textmining
co-expression
protein homology
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Score
IWS1Transcription elongation factor (TFIIS) family protein (502 aa)    
Predicted Functional Partners:
GTB1
Global transcription factor group B1 (1647 aa)
     
 
  0.994
AT1G63210
Transcription elongation factor SPT6 (1197 aa)
     
 
  0.972
BES1
BRI1-EMS-SUPPRESSOR 1; Positive brassinosteroid-signaling protein. Transcription factor that activates target gene expression by binding specifically to the DNA sequence 5’-CANNTG-3’(E box) through its N-terminal domain. Can bind individually to the promoter as a homodimer or synergistically as a heterodimer with BIM1, BIM2 or BIM3. The C-terminal domain is probably involved in transcriptional activation (357 aa)
       
 
  0.917
AT4G24300
Peptidase C50, separase (145 aa)
     
      0.835
RSW4
Separase; Cleaves SYN1, releasing sister chromatid cohesion. Required for the release of cohesin at anaphase I and anaphase II, whereas the release of cohesin during diplotene and diakinesis occurs in a separase-independent process. Essential for embryo and endosperm development. May play a role in centromeric heterochromatin structure/formation during early meiosis, non- homologous centromere association and radial microtubule system (RMS) formation. May regulate the mitosis-specific cyclin CYCB1-1 (2180 aa)
     
      0.835
SPT16
FACT complex subunit SPT16; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment o [...] (1074 aa)
     
 
  0.767
GTC2
Protein GTC2 (343 aa)
     
 
  0.749
NRPB2
DNA-directed RNA polymerase II subunit RPB2; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Second largest component of RNA polymerase II which synthesizes mRNA precursors and many functional non-coding RNAs. Proposed to contribute to the polymerase catalytic activity and forms the polymerase active center together with the largest subunit. Pol II is the central component of the basal RNA polymerase II transcription machinery. It is composed of mobile elements that move relative to each other. NRPB2 is [...] (1188 aa)
     
      0.748
ELF8
EARLY FLOWERING 8; Component of the PAF1 complex (PAF1C) which is involved in histone modifications such as methylation on histone H3 ’Lys-4’ (H3K4me3) (PubMed-20363855). Involved in regulation of flowering time. Required for the expression of the MADS box genes and flowering repressors FLC, AGL27/FLM and AGL31/MAF2 (PubMed-15520273, PubMed-15472079). Required for histone H3 trimethylation on ’Lys-4’ H3K4me3 at the FLC and AGL27/FLM loci (PubMed-15520273). Involved in the control of seed dormancy and germination (PubMed-21799800) (1091 aa)
     
 
  0.744
RPOB
RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (1072 aa)
     
      0.733
Your Current Organism:
Arabidopsis thaliana
NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress
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