Full Link:
STRINGSTRING
HDA15 HDA15 LUG LUG TPR10 TPR10 AT3G21060 AT3G21060 TRO TRO WSIP2 WSIP2 TPR9 TPR9 T21F11.18 T21F11.18 TPR6 TPR6 AT1G61700 AT1G61700 TPR15 TPR15
"TPR9" - Tetratricopeptide repeat 9 in Arabidopsis thaliana
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TPR9Tetratricopeptide repeat 9 (798 aa)    
Predicted Functional Partners:
TPR10
Tetratricopeptide repeat 10 (680 aa)
       
 
  0.925
TPR6
Tetratricopeptide repeat 6 (164 aa)
           
  0.922
TPR15
Tetratricopeptide repeat 15 (1108 aa)
     
   
  0.901
TRO
TRAUCO; Trithorax-group gene homolog required for early embryogenesis (PubMed-20118203, PubMed-21423667). Required for the expression of FLC and FLC homologs and represses flowering (PubMed-21423667). Required for proper leaf growth and development (PubMed-21423667). Part of COMPASS-like complexes responsible for H3K4 trimethylation, but not for di- or mono-methylation of histone H3 ’Lys-4’ (PubMed-21423667). Binds to target loci chromatin, increasing H3K4 trimethylation and causing activation of the gene (PubMed-21423667) (509 aa)
     
 
  0.722
AT3G21060
RbBP5 LIKE; Promotes the expression of FLC and FLC homologs to repress the floral transition (547 aa)
     
 
  0.711
LUG
LEUNIG; Transcription repressor subunit of the SEU-LUG transcriptional corepressor of the C class floral homeotic gene AGAMOUS during the early stages of floral meristem development. Is part of the A class cadastral complex that define the boundaries between the A and C class homeotic genes expression and function. Interacts together with APETALA2 and SEUSS to repress AGAMOUS expression. Also plays a role in ovule and pollen development (PubMed-11782418, PubMed-15277686, PubMed-7743940). Implicated in embryo and floral development (PubMed-18390806). Involved in post- synthesis cell wal [...] (969 aa)
     
 
  0.687
T21F11.18
TOPLESS-related 1; Transcriptional corepressor. Activates TIR-NB-LRR R protein-mediated immune responses through repression of negative regulators such as CNGC2/DND1 (PubMed-20647385). Negative regulator of jasmonate responses (By similarity) (1120 aa)
     
 
  0.677
AT1G61700
DNA-directed RNA polymerases II subunit L (71 aa)
     
 
  0.674
HDA15
Histone deacetylase 15; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes (By similarity) (564 aa)
   
  0.666
WSIP2
Topless-related protein 4; Transcriptional corepressor. Negative regulator of jasmonate responses (By similarity) (1137 aa)
     
 
  0.660
Your Current Organism:
Arabidopsis thaliana
NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress
Server load: low (2%)