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RECQI1 RECQI1 AT1G34380 AT1G34380 AT4G32700 AT4G32700 RECQSIM RECQSIM RecQl3 RecQl3 MRE11 MRE11 PCNA1 PCNA1 LIG6 LIG6 RECQL2 RECQL2 PCNA2 PCNA2 RECQ4B RECQ4B
"AT1G34380" - 5'-3' exonuclease-like protein in Arabidopsis thaliana
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Neighborhood
Gene Fusion
Cooccurence
Coexpression
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[Homology]
Score
AT1G343805’-3’ exonuclease-like protein (347 aa)    
Predicted Functional Partners:
PCNA2
Proliferating cell nuclear antigen 2; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase’s processibility during elongation of the leading strand (By similarity). May be involved in UV resistance (264 aa)
     
 
  0.947
PCNA1
Proliferating cellular nuclear antigen 1; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase’s processibility during elongation of the leading strand (263 aa)
     
 
  0.947
LIG6
DNA LIGASE 6 (1396 aa)
     
 
  0.849
MRE11
MEIOTIC RECOMBINATION 11; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand- specific 3’-5’ exonuclease activity. Also involved in meiotic DSB processing (By similarity) (720 aa)
   
 
  0.789
AT4G32700
DNA polymerase theta subunit; Required for regulated cell division and differentiation in meristems and embryos, thus modulating adaxial-abaxial polarity. Regulates the progression of cell cycle and DNA replication (e.g. G2/M progression and intrachromosomal recombination) and the expression of genes during development, especially genes nearby the Helitron transposons (2154 aa)
   
 
  0.766
RECQSIM
DNA helicase; Plant specific 3’-5’ DNA helicase that may play a role in the repair of DNA (858 aa)
   
 
  0.752
RecQl3
ATP-dependent DNA helicase Q-like 3; 3’-5’ DNA helicase that may play a role in the repair of DNA. Exhibits an ATP or dATP-dependent DNA-helicase activity. Can not use GTP/dGTP, CTP/dCTP or UTP/dUTP as nucleotide cofactors. Catalyzes DNA strand annealing. On nicked Holliday junctions, unwinds the lagging strand. Can not act on intact Holliday junctions (713 aa)
   
 
  0.752
RECQI1
RECQ helicase l1; 3’-5’ DNA helicase that may play a role in the repair of DNA (606 aa)
   
 
  0.752
RECQ4B
RECQ helicase L4B; 3’-5’ DNA helicase that may play a role in the repair of DNA (By similarity). Required to promote but not to suppress crossovers (1150 aa)
   
 
  0.752
RECQL2
RECQ helicase L2; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. The Mediator complex, having a compact conformation in its free form, is recruited to promoters by direct interactions with regulatory proteins and serves for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (705 aa)
   
 
  0.752
Your Current Organism:
Arabidopsis thaliana
NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress
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