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AT5G49990 AT5G49990 AT5G62890 AT5G62890 AZG1 AZG1 AZG2 AZG2 AT5G41800 AT5G41800 AT5G42420 AT5G42420 PUP11 PUP11 UPS2 UPS2 AT5G41330 AT5G41330 PYD1 PYD1 AT5G25420 AT5G25420
"PUP11" - Purine permease 11 in Arabidopsis thaliana
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PUP11Purine permease 11 (379 aa)    
Predicted Functional Partners:
AT5G49990
Nucleobase-ascorbate transporter 5 (528 aa)
           
  0.922
AT5G25420
Xanthine/uracil/vitamin C permease (419 aa)
           
  0.922
AT5G41800
Transmembrane amino acid transporter family protein; May be involved in the transport of GABA (452 aa)
           
  0.869
AT5G42420
Nucleotide-sugar transporter family protein (350 aa)
           
  0.865
AT5G62890
Nucleobase-ascorbate transporter 6 (532 aa)
           
  0.861
AZG2
AZA-GUANINE RESISTANT2; Transports natural purines (adenine and guanine) as well as purine analogs. Confers sensitivity to 8-azaadenine and 8- azaguanine (8-azg) (530 aa)
           
  0.861
AT5G41330
BTB/POZ domain with WD40/YVTN repeat-like protein; May act as a substrate-specific adapter of an E3 ubiquitin-protein ligase complex (CUL3-RBX1-BTB) which mediates the ubiquitination and subsequent proteasomal degradation of target proteins (458 aa)
           
  0.809
PYD1
Pyrimidine 1; Involved in pyrimidine base degradation. Catalyzes the reduction of uracil to 5,6-dihydrouracil (DHU) by using NADH as a specific cosubstrate and the reduction of thymine to 5,6- dihydrothymine (DHT). Involved in the recycling of nitrogen from nucleobases to general nitrogen metabolism (426 aa)
           
  0.808
UPS2
Ureide permease 2; Proton-coupled transporter that ransports a wide spectrum of oxo derivatives of heterocyclic nitrogen compounds, including allantoin, uric acid and xanthine, but not adenine. Mediates high affinity transport of uracil and 5-fluorouracil (a toxic uracil analog). Mediates transport of free pyrimidines and may function during early seedling development in salvage pathways, by the utilization of pyrimidines from seed storage tissue (398 aa)
           
  0.710
AZG1
AZA-guanine resistant1; Transports natural purines (adenine and guanine) as well as purine analogs. Confers sensitivity to 8-azaadenine and 8- azaguanine (8-azg) (579 aa)
           
  0.709
Your Current Organism:
Arabidopsis thaliana
NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress
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