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RECQL2 RECQL2 AT5G20170 AT5G20170 SWP SWP SDN3 SDN3 PRP40A PRP40A CDC5 CDC5 U1-70K U1-70K DOT2 DOT2 UNE6 UNE6 AT2G43370 AT2G43370 AT1G60200 AT1G60200
"PRP40A" - pre-mRNA-processing protein 40A in Arabidopsis thaliana
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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PRP40Apre-mRNA-processing protein 40A; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. The Mediator complex, having a compact conformation in its free form, is recruited to promoters by direct interactions with regulatory proteins and serves for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. I [...] (958 aa)    
Predicted Functional Partners:
AT1G60200
RNA-binding protein 25 (899 aa)
     
 
  0.976
DOT2
DEFECTIVELY ORGANIZED TRIBUTARIES 2; Plays a role in root, shoot and flower development. Probably required for normal root and shoot meristem organization and maintenance and the proper expression of PIN and PLT genes (PubMed-19000164). Involved in leaf vasculature patterning (PubMed-18643975) (820 aa)
     
 
  0.968
CDC5
Cell division cycle 5; Component of the MAC complex that probably regulates defense responses through transcriptional control and thereby is essential for plant innate immunity. Possesses a sequence specific DNA sequence ’CTCAGCG’ binding activity. Involved in mRNA splicing and cell cycle control. May also play a role in the response to DNA damage (844 aa)
     
 
  0.967
U1-70K
Encodes U1 snRNP 70K; Mediates the splicing of pre-mRNA by binding to the loop I region of U1-snRNA (427 aa)
     
 
  0.966
AT2G43370
RNA-binding (RRM/RBD/RNP motifs) family protein; May facilitate 5’ splice site recognition in the minor spliceosome. May be involved in interactions with components of the major spliceosome bound to the pyrimidine tract of an upstream U2-type intron (333 aa)
     
 
  0.964
RECQL2
RECQ helicase L2; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. The Mediator complex, having a compact conformation in its free form, is recruited to promoters by direct interactions with regulatory proteins and serves for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (705 aa)
     
 
  0.964
SDN3
Small RNA degrading nuclease 3; 3’-5’ exonuclease degrading single-stranded small RNAs (782 aa)
     
    0.937
UNE6
LUC7 related protein (402 aa)
     
 
  0.937
AT5G20170
RNA polymerase II transcription mediator; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. The Mediator complex, having a compact conformation in its free form, is recruited to promoters by direct interactions with regulatory proteins and serves for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (653 aa)
     
 
    0.935
SWP
STRUWWELPETER; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. The Mediator complex, having a compact conformation in its free form, is recruited to promoters by direct interactions with regulatory proteins and serves for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. Involved in definin [...] (1703 aa)
         
  0.927
Your Current Organism:
Arabidopsis thaliana
NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress
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