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RHL2 RHL2 AT1G22060 AT1G22060 BIN4 BIN4 AT3G42860 AT3G42860 TOP6B TOP6B RHL1 RHL1 REN1 REN1 GL2 GL2 RHD6 RHD6 EXO70H2 EXO70H2 COW1 COW1
"RHL1" - ROOT HAIRLESS 1 in Arabidopsis thaliana
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Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RHL1ROOT HAIRLESS 1 (386 aa)    
Predicted Functional Partners:
RHL2
ROOT HAIRLESS 2; Component of the DNA topoisomerase VI involved in chromatin organization and progression of endoreduplication cycles. Relaxes both positive and negative superturns and exhibits a strong decatenase activity. Involved in cell-elongation processes (427 aa)
       
 
  0.908
TOP6B
Topoisomerase 6 subunit B; Component of the DNA topoisomerase VI involved in chromatin organization and progression of endoreduplication cycles. Relaxes both positive and negative superturns and exhibits a strong decatenase activity. The B subunit binds ATP. Involved in cell-elongation processes (670 aa)
     
   
  0.866
AT3G42860
CCHC-type zinc knuckle protein; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5’-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3’-OH DNA strand (372 aa)
     
   
  0.815
AT1G22060
Uncharacterized protein (1999 aa)
     
   
  0.750
RHD6
ROOT HAIR DEFECTIVE6 (298 aa)
           
  0.734
BIN4
DNA-binding protein BIN4; Component of the DNA topoisomerase VI complex. Binds to DNA. Required for chromatin organization and progression of endoreduplication cycles. The loss of BIN4 activates the ATM- and ATR-dependent DNA damage responses in postmitotic cells and induces the ectopic expression of the mitotic G2/M-specific cyclin B1;1 gene in non-dividing cells (454 aa)
       
 
  0.692
COW1
CAN OF WORMS1; Required for transport of secretory proteins from the Golgi complex (By similarity). Catalyzes the transfer of phosphatidylinositol and phosphatidylcholine between membranes in vitro. Plays a role in root hair tip elongation as a key regulator of polarized membrane trafficking. May promote the PtdIns(4,5)P2 synthesis and organization in root hair membrane (554 aa)
           
  0.635
REN1
ROP1 ENHANCER 1; Acts as a GTPase activator for the Rac-type GTPase by converting it to an inactive GDP-bound state. Maintains the global inactivation of ARAC11/ROP1 at the apex in pollen tubes in order to regulate the polar cell growth (933 aa)
           
  0.607
EXO70H2
Exocyst complex component 7 (637 aa)
           
  0.551
GL2
GLABRA 2; Probable transcription factor required for correct morphological development and maturation of trichomes as well as for normal development of seed coat mucilage. Regulates the frequency of trichome initiation and determines trichome spacing (776 aa)
           
  0.550
Your Current Organism:
Arabidopsis thaliana
NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress
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