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APG8A APG8A ATG8B ATG8B ATG13 ATG13 ATG8F ATG8F AT3G18770 AT3G18770 AT1G49180 AT1G49180 PUR4 PUR4 TIL2 TIL2 ICU2 ICU2 POLD2 POLD2 TIL1 TIL1
"AT1G49180" - Protein kinase-like protein in Arabidopsis thaliana
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
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experimentally determined
Predicted Interactions
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gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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AT1G49180Protein kinase-like protein; Serine/threonine protein kinase involved in autophagy. The ATG1-ATG13 protein kinase complex regulates downstream events required for autophagosome enclosure and/or vacuolar delivery (408 aa)    
Predicted Functional Partners:
POLD2
DNA polymerase delta subunit 2; The function of the small subunit is not yet clear (441 aa)
     
 
  0.978
TIL2
TILTED 2; DNA polymerase II participates in chromosomal DNA replication (By similarity). Involved in the determination of cell fate during plant embryogenesis. Contributes to the flowering time repression (2138 aa)
     
 
  0.956
TIL1
TILTED 1; DNA polymerase II participates in chromosomal DNA replication. Required for the timing and determination of cell fate during plant embryogenesis and root pole development, by promoting cell cycle and cell type patterning. Necessary for proper shoot (SAM) and root apical meristem (RAM) functions. Involved in maintaining epigenetic states, controlling hypersensitive response (HR), and mediating abscisic acid (ABA) signaling. Required for flowering repression through a mechanism involving epigenetic gene silencing. May participate in processes involved in chromatin-mediated cell [...] (2161 aa)
     
 
  0.956
ATG13
Autophagy-related 13; Involved in autophagy in a nutritional condition dependent manner. The ATG1-ATG13 protein kinase complex regulates downstream events required for autophagosome enclosure and/or vacuolar delivery. Becomes a target of autophagy under nutrient starvation. Connects autophagy to plant nutritional status (618 aa)
     
 
  0.951
ICU2
INCURVATA2; Polymerase alpha in a complex with DNA primase is a replicative polymerase (1524 aa)
     
 
  0.951
AT3G18770
Autophagy-related protein 13; Involved in autophagy in a nutritional condition dependent manner. The ATG1-ATG13 protein kinase complex regulates downstream events required for autophagosome enclosure and/or vacuolar delivery. Becomes a target of autophagy under nutrient starvation (By similarity). Connects autophagy to plant nutritional status (PubMed-21984698) (625 aa)
     
 
  0.945
PUR4
Purine biosynthesis 4; Essential to the male gametophyte development. Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate (1407 aa)
       
      0.920
APG8A
AUTOPHAGY 8A; Ubiquitin-like modifier involved in cytoplasm to vacuole transport (Cvt) vesicles and autophagosomes formation. May mediate the delivery of the vesicles and autophagosomes to the vacuole via the microtubule cytoskeleton (137 aa)
     
 
  0.839
ATG8F
Autophagy 8f; Ubiquitin-like modifier involved in cytoplasm to vacuole transport (Cvt) vesicles and autophagosomes formation. May mediate the delivery of the vesicles and autophagosomes to the vacuole via the microtubule cytoskeleton (By similarity) (121 aa)
     
 
  0.839
ATG8B
Autophagy 8b; Ubiquitin-like modifier involved in cytoplasm to vacuole transport (Cvt) vesicles and autophagosomes formation. May mediate the delivery of the vesicles and autophagosomes to the vacuole via the microtubule cytoskeleton (By similarity) (122 aa)
     
 
  0.839
Your Current Organism:
Arabidopsis thaliana
NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress
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