Full Link:
STRINGSTRING
FKBP12 FKBP12 AT2G20050 AT2G20050 HSF1 HSF1 RAPTOR1 RAPTOR1 TOR TOR LST8-1 LST8-1 RAPTOR2 RAPTOR2 AT1G79190 AT1G79190 PK1 PK1 LST8-2 LST8-2 S6K2 S6K2
"TOR" - Target of rapamycin in Arabidopsis thaliana
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TORTarget of rapamycin; Essential cell growth regulator that controls development from early embryo to seed production. Controls plant growth in environmental stress conditions. Acts through the phosphorylation of downstream effectors that are recruited by the binding partner RAPTOR. Acts by activating transcription, protein synthesis and ribosome biogenesis, and inhibiting mRNA degradation and autophagy (2481 aa)    
Predicted Functional Partners:
RAPTOR1
Regulatory associated protein of mTOR; Probable component of the plant TOR kinase pathway that recruits substrates for TOR. Modulates plant cell growth and regulates the activity of ATPK1 kinase in response to osmotic stress (1344 aa)
     
  0.999
RAPTOR2
RAPTOR2; Probable component of the plant TOR kinase pathway (1336 aa)
     
  0.999
PK1
Protein-serine kinase 1; Downstream effector of TOR signaling pathway involved in osmotic stress response. Could be involved in the control of plant growth and development. Phosphorylates the ribosomal proteins P14, P16 and S6. Functions as a repressor of cell proliferation and required for maintenance of chromosome stability and ploidy levels through the RBR1-E2F pathway (465 aa)
     
  0.999
LST8-1
Lethal with Sec Thirteen 8-1 (305 aa)
       
  0.999
LST8-2
Lethal with Sec Thirteen 8-2 (313 aa)
       
  0.998
S6K2
Serine/threonine protein kinase 2; Downstream effector of TOR signaling pathway. May be involved in adaptation of plant to cold or high-salt conditions (471 aa)
     
  0.997
FKBP12
FK506-binding protein 12; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides (By similarity). Mediates rapamycin inactivation of TOR protein kinase activity (112 aa)
       
  0.996
AT2G20050
Protein phosphatase 2C and cyclic nucleotide-binding/kinase domain-containing protein (1094 aa)
     
 
  0.976
AT1G79190
Uncharacterized protein (1335 aa)
     
 
  0.966
HSF1
Heat shock factor 1; Transcriptional activator that specifically binds DNA sequence 5’-AGAAnnTTCT-3’ known as heat shock promoter elements (HSE) (495 aa)
     
  0.941
Your Current Organism:
Arabidopsis thaliana
NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress
Server load: low (1%)