Co-purification, co-crystallization, Yeast2Hybrid, Genetic Interactions, etc ... as imported from primary sources.
Groups of genes that are frequently observed in each other's genomic neighborhood.
Automated, unsupervised textmining - searching for proteins that are frequently mentioned together.
Genes that are sometimes fused into single open reading frames.
STRING allows inspection of the interaction evidence for any given network. Choose any of the viewers above (disabled if not applicable in your network).
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
colored nodes: query proteins and first shell of interactors
white nodes: second shell of interactors
empty nodes: proteins of unknown 3D structure
filled nodes: some 3D structure is known or predicted
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
from curated databases
Uncharacterized protein (227 aa)
Predicted Functional Partners:
Uncharacterized protein (440 aa)
FBD-associated F-box protein (360 aa)
SKP1-like 15; Involved in ubiquitination and subsequent proteasomal degradation of target proteins. Together with CUL1, RBX1 and a F- box protein, it forms a SCF E3 ubiquitin ligase complex. The functional specificity of this complex depends of the type of F- box protein. In the SCF complex, it serves as an adapter that links the F-box protein to CUL1 (By similarity) (177 aa)
F-box and associated interaction domain-containing protein (394 aa)
F-box and associated interaction domain-containing protein (373 aa)
Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin-like protein (123 aa)
Self-incompatibility S1 family protein (141 aa)
B-block binding subunit of TFIIIC (1729 aa)
RING/U-box superfamily protein (185 aa)
F-box and associated interaction domain-containing protein (548 aa)
Your Current Organism:
NCBI taxonomy Id: 3702 Other names: A. thaliana, Arabidopsis thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress