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ERO1 ERO1 ERO2 ERO2 DER2.2 DER2.2 DER1 DER1 DER2.1 DER2.1 GDI GDI AT1G50950 AT1G50950 AT1G12070 AT1G12070 APC6 APC6 AT5G57300 AT5G57300 ALF5 ALF5
"AT1G50950" - Thioredoxin protein with domain of unknown function in Arabidopsis thaliana
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Score
AT1G50950Thioredoxin protein with domain of unknown function (DUF1692) (484 aa)    
Predicted Functional Partners:
AT5G57300
Ubiquinone biosynthesis methyltransferase COQ5; Methyltransferase required for the conversion of 2- polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3- methyl-6-methoxy-1,4-benzoquinol (DMQH2) (288 aa)
     
   
  0.744
ALF5
ABERRANT LATERAL ROOT FORMATION 5; Required for protection of the roots from inhibitory compounds. When expressed in a heterologous system, confers resistance to tetramethylammonium chloride (477 aa)
           
  0.670
AT1G12070
Immunoglobulin E-set superfamily protein (223 aa)
           
  0.630
GDI
RAB GDP-dissociation inhibitor; Regulates the GDP/GTP exchange reaction of most RAB proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP (445 aa)
           
  0.600
APC6
Anaphase promoting complex 6; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin-protein ligase complex that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex controls several key steps in the cell cycle by mediating ubiquitination and subsequent degradation of target proteins such as cyclins. The APC/C complex is required for the female gametophyte development and is involved in several aspect of development by controlling cell division and cell elongation. Involved in the control of endoreduplication (543 aa)
     
   
  0.578
DER1
DERLIN-1; May be involved in the degradation process of specific misfolded endoplasmic reticulum (ER) luminal proteins (266 aa)
     
      0.508
DER2.1
DERLIN-2.1; May be involved in the degradation process of specific misfolded endoplasmic reticulum (ER) luminal proteins (244 aa)
     
      0.508
DER2.2
DERLIN-2.2; May be involved in the degradation process of specific misfolded endoplasmic reticulum (ER) luminal proteins (244 aa)
     
      0.508
ERO2
Endoplasmic oxidoreductin-2; Essential oxidoreductase that oxidizes proteins in the endoplasmic reticulum to produce disulfide bonds. Acts by oxidizing directly PDI isomerase through a direct disulfide exchange. Does not act as a direct oxidant of folding substrate, but relies on PDI to transfer oxidizing equivalent. Does not oxidize all PDI related proteins, suggesting that it can discriminate between PDI and related proteins. Its reoxidation probably involves electron transfer to molecular oxygen via FAD. Acts independently of glutathione. May be responsible for a significant proport [...] (479 aa)
       
 
  0.501
ERO1
Endoplasmic oxidoreductin-1; Essential oxidoreductase that oxidizes proteins in the endoplasmic reticulum to produce disulfide bonds. Acts by oxidizing directly PDI isomerase through a direct disulfide exchange. Does not act as a direct oxidant of folding substrate, but relies on PDI to transfer oxidizing equivalent. Does not oxidize all PDI related proteins, suggesting that it can discriminate between PDI and related proteins. Its reoxidation probably involves electron transfer to molecular oxygen via FAD. Acts independently of glutathione. May be responsible for a significant proport [...] (469 aa)
       
 
  0.501
Your Current Organism:
Arabidopsis thaliana
NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress
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