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NFU1 NFU1 NFS1 NFS1 CPNIFS CPNIFS ISU1 ISU1 NFU5 NFU5 CPISCA CPISCA HCF101 HCF101 ABCB25 ABCB25 AT5G03905 AT5G03905 CXIP2 CXIP2 emb1345 emb1345
"NFU5" - NifU-like protein 5 in Arabidopsis thaliana
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NFU5NifU-like protein 5; Molecular scaffold for [Fe-S] cluster assembly of mitochondrial iron-sulfur proteins (275 aa)    
Predicted Functional Partners:
NFU1
NifU-like protein 1; Molecular scaffold for [Fe-S] cluster assembly of chloroplastic iron-sulfur proteins (231 aa)
   
     
  0.966
NFS1
Cysteine desulfurase 1; Catalyzes the removal of elemental sulfur from cysteine to produce alanine. Supplies the inorganic sulfur for iron-sulfur (Fe-S) clusters (453 aa)
   
  0.937
CPNIFS
Cysteine desulfurase 2; Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine (PubMed-12033984, PubMed-16455656). Supplies the inorganic sulfur for iron-sulfur (Fe-S) clusters (PubMed-15480755, PubMed-17372218). Required for the maturation of all plastidic Fe-S proteins and, thus, essential for plant growth (PubMed-17372218) (463 aa)
       
  0.891
ISU1
SufE/NifU family protein; Scaffold protein for the de novo synthesis of iron- sulfur (Fe-S) clusters within mitochondria, which is required for maturation of both mitochondrial and cytoplasmic [2Fe-2S] and [4Fe-4S] proteins (PubMed-15507320, PubMed-17417719). First, a [2Fe-2S] cluster is transiently assembled on the scaffold protein ISCU (ISU1, ISU2 or ISU3). In a second step, the cluster is released from ISCU, transferred to a glutaredoxin, followed by the formation of mitochondrial [2Fe-2S] proteins, the synthesis of [4Fe-4S] clusters and their target-specific insertion into the reci [...] (167 aa)
   
 
  0.890
AT5G03905
Iron-sulfur assembly protein IscA-like 2; Involved in the assembly of mitochondrial iron-sulfur proteins. Probably involved in the binding of an intermediate of Fe/S cluster assembly (By similarity) (158 aa)
   
 
  0.853
CPISCA
Iron-sulfur assembly protein IscA; Involved in the assembly of chloroplastic iron-sulfur proteins. Is able to transfer iron-sulfur clusters to apo- ferredoxin (180 aa)
   
 
  0.782
emb1345
Embryo defective 1345; Essential component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery. Required for the maturation of extramitochondrial Fe/S proteins (352 aa)
     
   
  0.739
HCF101
ATP binding protein; Required for photosystem I (PSI) biosynthesis and assembly. May serve as a chloroplast scaffold protein that specifically assembles iron-sulfur (4Fe-4S) clusters and transfers them to the chloroplast PSI and ferredoxin-thioredoxin (FTR) complexes. Can assemble a 4Fe-4S cluster and transfer it to apoproteins in yeast cells. Probably not required for assembly or stability of plastidic 2Fe-2S clusters (532 aa)
   
 
  0.725
ABCB25
ATP-binding cassette B25; Performs an essential function in the generation of cytoplasmic iron-sulfur proteins by mediating export of Fe/S cluster precursors synthesized by NFS1 and other mitochondrial proteins. Not required for mitochondrial and plastid Fe-S enzymes. Probably involved in the export of cyclic pyranopterin monophosphate (cPMP) from mitochondria into the cytosol. Mediates glutathione-dependent resistance to heavy metals such as cadmium and lead, as well as their transport from roots to leaves. Regulates nonprotein thiols (NPSH) and the cellular level of glutathione (GSH) (728 aa)
     
   
  0.708
CXIP2
CAX-interacting protein 2; May only reduce GSH-thiol disulfides, but not protein disulfides (Probable). Participates probably to the maturation of iron-sulfur proteins and to the regulation of the redox state of the BOLA proteins (Probable). The GRXS16-BOLA1 heterodimer binds a labile, oxygen sensitive iron-sulfur cluster (PubMed-24714563). Able to cleave linearized DNA in vitro (PubMed-23690600) (293 aa)
   
   
  0.698
Your Current Organism:
Arabidopsis thaliana
NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress
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