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At1g80820 At1g80820 HCT HCT CYP84A1 CYP84A1 IRX4 IRX4 PAL3 PAL3 CCoAOMT1 CCoAOMT1 4CL1 4CL1 PAL2 PAL2 C4H C4H PAL4 PAL4 PAL1 PAL1
"4CL1" - 4-coumarate:CoA ligase 1 in Arabidopsis thaliana
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second shell of interactors
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Known Interactions
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experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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4CL14-coumarate-CoA ligase 1; Produces CoA thioesters of a variety of hydroxy- and methoxy-substituted cinnamic acids, which are used to synthesize several phenylpropanoid-derived compounds, including anthocyanins, flavonoids, isoflavonoids, coumarins, lignin, suberin and wall- bound phenolics (561 aa)    
Predicted Functional Partners:
PAL1
PHE ammonia lyase 1; This is a key enzyme of plant metabolism catalyzing the first reaction in the biosynthesis from L-phenylalanine of a wide variety of natural products based on the phenylpropane skeleton (725 aa)
   
 
  0.996
C4H
Cinnamate-4-hydroxylase; Controls carbon flux to pigments essential for pollination or UV protection, to numerous pytoalexins synthesized by plants when challenged by pathogens, and to lignins (505 aa)
   
 
  0.996
CCoAOMT1
Caffeoyl coenzyme A O-methyltransferase 1; Methylates caffeoyl-CoA to feruloyl-CoA. Has a very low activity with caffeic acid and esculetin. Involved in scopoletin biosynthesis in roots (259 aa)
     
  0.991
HCT
hydroxycinnamoyl-CoA shikimate/quinate hydroxycinnamoyl transferase; Acyltransferase involved in the biosynthesis of lignin. Accepts caffeoyl-CoA and p-coumaroyl-CoA as substrates and transfers the acyl group on both shikimate and quinate acceptors (433 aa)
     
 
  0.991
IRX4
Cinnamoyl coa reductase 1; Involved in the latter stages of lignin biosynthesis. Catalyzes one of the last steps of monolignol biosynthesis, the conversion of cinnamoyl-CoAs into their corresponding cinnamaldehydes (344 aa)
   
 
  0.989
PAL2
Phenylalanine ammonia-lyase 2; This is a key enzyme of plant metabolism catalyzing the first reaction in the biosynthesis from L-phenylalanine of a wide variety of natural products based on the phenylpropane skeleton (717 aa)
   
 
  0.989
CYP84A1
Ferulic acid 5-hydroxylase 1 (520 aa)
   
 
  0.986
PAL4
Phenylalanine ammonia-lyase 4; This is a key enzyme of plant metabolism catalyzing the first reaction in the biosynthesis from L-phenylalanine of a wide variety of natural products based on the phenylpropane skeleton (707 aa)
   
 
  0.974
At1g80820
Cinnamoyl coa reductase; Cinnamoyl-CoA reductase probably involved in the formation of phenolic compounds associated with the hypersensitive response. Seems not to be involved in lignin biosynthesis (332 aa)
   
 
  0.973
PAL3
Phenylalanine ammonia-lyase 3; This is a key enzyme of plant metabolism catalyzing the first reaction in the biosynthesis from L-phenylalanine of a wide variety of natural products based on the phenylpropane skeleton (698 aa)
       
  0.973
Your Current Organism:
Arabidopsis thaliana
NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress
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