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SIR SIR APR1 APR1 PSBG PSBG RDH2 RDH2 SOX SOX GLY3 GLY3 APR2 APR2 CNX5 CNX5 GLX1 GLX1 AT1G67280 AT1G67280 AT2G32090 AT2G32090
"GLY3" - Glyoxalase II 3 in Arabidopsis thaliana
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second shell of interactors
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Known Interactions
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experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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GLY3Glyoxalase II 3; Sulfur dioxygenase that plays an essential role in hydrogen sulfide catabolism in the mitochondrial matrix. Hydrogen sulfide (H(2)S) gives rise to cysteine persulfide residues. ETHE1 consumes molecular oxygen to catalyze the oxidation of the persulfide, once it has been transferred to a thiophilic acceptor, such as glutathione (R-SSH). Plays an important role in metabolic homeostasis in mitochondria by metabolizing hydrogen sulfide and preventing the accumulation of supraphysiological H(2)S levels that have toxic effects, due to the inhibition of cytochrome c oxidase. [...] (294 aa)    
Predicted Functional Partners:
SOX
Sulfite oxidase; Probably involved in sulfite oxidative detoxification (393 aa)
         
  0.905
SIR
Sulfite reductase; Essential protein with sulfite reductase activity required in assimilatory sulfate reduction pathway during both primary and secondary metabolism and thus involved in development and growth (642 aa)
         
  0.902
RDH2
Rhodanese homologue 2; Catalyzes the transfer of a sulfur ion from a donor to cyanide or to other thiol compounds. Substrate preference is 3- mercaptopyruvate > thiosulfate. Involved in embryo and seed development (342 aa)
       
    0.901
APR1
APS reductase 1; Reduces sulfate for Cys biosynthesis. Substrate preference is adenosine-5’-phosphosulfate (APS) >> 3’- phosphoadenosine-5’-phosphosulfate (PAPS). Uses glutathione or DTT as source of protons (465 aa)
         
    0.900
APR2
5’-adenylylsulfate reductase 2; Reduces sulfate for Cys biosynthesis. Substrate preference is adenosine-5’-phosphosulfate (APS) >> 3’- phosphoadenosine-5’-phosphosulfate (PAPS). Uses glutathione or DTT as source of protons (454 aa)
         
    0.900
GLX1
Glyoxalase I homolog; Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione (322 aa)
   
 
  0.774
AT2G32090
Lactoylglutathione lyase / glyoxalase I-like protein (135 aa)
   
 
  0.688
AT1G67280
Putative lactoylglutathione lyase, chloroplast; Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione (350 aa)
   
 
  0.688
CNX5
Sulfurtransferase MOCS3; Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln). Also essential during biosynthesis of the molybdenum cofactor. Acts by mediating the C-terminal thiocarboxylation of sulfur carriers URM1 and MOCS2A. Its N-terminus first activates URM1 and MOCS2A as acyl-adenylates (-COAMP), then the persulfide sulfur on the catalytic cysteine is transferred to URM1 and MOCS2A to form thiocarboxylation (-COSH) of their C-terminus. The reaction probably involves hydrogen sulfide that is generated from th [...] (464 aa)
   
   
  0.682
PSBG
Photosystem II reaction center protein G; NDH shuttles electrons from NAD(P)H-plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient (225 aa)
     
      0.667
Your Current Organism:
Arabidopsis thaliana
NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress
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