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SNF7.1 SNF7.1 SNF7.2 SNF7.2 VPS46.2 VPS46.2 CR4 CR4 AT4G02010 AT4G02010 ATML1 ATML1 DEK1 DEK1 AT5G04170 AT5G04170 AT3G10300 AT3G10300 AT2G27480 AT2G27480 AT1G52640 AT1G52640
"DEK1" - DEFECTIVE KERNEL 1 in Arabidopsis thaliana
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Gene Fusion
Cooccurence
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Databases
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[Homology]
Score
DEK1DEFECTIVE KERNEL 1; Essential protein involved in epiderm development. Required for aleurone cell development in the endosperm probably by maintaining and restricting the aleurone and embryonic epidermal L1 cell-layer fates as well as meristems organization. Involved in the maintenance of adaxial/abaxial axis information in developing leaves, probably by regulating cell proliferation and expansion. Does not need calcium ions to be active. Required for the formation of giant cells in sepals by determining cell fate and promoting endoreplication (2179 aa)    
Predicted Functional Partners:
AT5G04170
Calcium-binding EF-hand family protein; Potential calcium sensor (354 aa)
       
  0.911
AT3G10300
Calcium-binding EF-hand family protein; Potential calcium sensor (335 aa)
       
  0.911
AT2G27480
Calcium-binding EF-hand family protein; Potential calcium sensor (228 aa)
       
  0.911
CR4
Crinkly4; Controls formative cell division in meristems, including root tips and lateral root initiation zones of the pericycle, in response to CLE40 signal. Acts with CLE40p peptide as a ligand- receptor pair in a signal transduction pathway, coordinating movement of the root tip and organization of cell divisions in the root meristem. Required during embryogenesis and development, probably for the differentiation of protoderm and epidermal cells. Involved in the regulation of cellular organization during the development of sepal margins and ovule integument outgrowth. Can phosphoryla [...] (895 aa)
     
  0.904
SNF7.1
SNF7 family protein; Component of the ESCRT-III complex, which is required for multivesicular bodies (MVBs) formation and sorting of endosomal cargo proteins into MVBs. The ESCRT-III complex is probably involved in the concentration of MVB cargo (By similarity) (219 aa)
       
 
  0.711
SNF7.2
SNF7 family protein; Component of the ESCRT-III complex, which is required for multivesicular bodies (MVBs) formation and sorting of endosomal cargo proteins into MVBs. The ESCRT-III complex is probably involved in the concentration of MVB cargo (By similarity) (213 aa)
       
 
  0.711
VPS46.2
SNF7-like protein; Involved in ESCRT-dependent multivesicular body (MVB) formation and sorting of endosomal cargo proteins into MVBs. Mediates the MVB sorting of the auxin carriers PIN1, PIN2 and AUX1. Required for embryonic axis establishment and seedling growth (PubMed-19304934). Required for autophagic degradation of plastid proteins. Promotes the efficient sequestration of cargo from plastids into autophagosomes. Mediates the efficient delivery of autophagic plastid bodies to the vacuole, but not into the cytoplasm (PubMed-25649438) (203 aa)
       
 
  0.691
ATML1
MERISTEM LAYER 1; Probable transcription factor involved in cell specification and pattern formation during embryogenesis. Binds to the L1 box DNA sequence 5’-TAAATG[CT]A-3’. Plays a role in maintaining the identity of L1 cells, possibly by interacting with their L1 box or other target-gene promoters. Functionally redundant to PDF2 (762 aa)
     
   
  0.691
AT4G02010
Protein kinase family protein (725 aa)
     
  0.659
AT1G52640
Pentatricopeptide repeat-containing protein (523 aa)
           
  0.635
Your Current Organism:
Arabidopsis thaliana
NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress
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