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VIP2 VIP2 IMPA-4 IMPA-4 PBRP PBRP IMPA-1 IMPA-1 AT5G37490 AT5G37490 PP2-B14 PP2-B14 VIP1 VIP1 PP2-B13 PP2-B13 MPK3 MPK3 CMPG1 CMPG1 SKP1 SKP1
"PP2-B14" - Phloem protein 2-B14 in Arabidopsis thaliana
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Known Interactions
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experimentally determined
Predicted Interactions
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gene co-occurrence
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textmining
co-expression
protein homology
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PP2-B14Phloem protein 2-B14; Component of SCF(VBF) E3 ubiquitin ligase complexes, which mediate the ubiquitination and subsequent proteasomal degradation of target proteins such as VIP1 and Agrobacterium virE2, after their implication in T-DNA translocation to the host nucleus (can functionally replace Agrobacterium VirF). Required during Agrobacterium-induced tumor formation (282 aa)    
Predicted Functional Partners:
VIP1
VIRE2-interacting protein 1; Transcription activator that binds specifically to the VIP1 response elements (VREs) DNA sequence 5’-ACNGCT-3’ found in some stress genes (e.g. TRX8 and MYB44), when phosphorylated/activated by MPK3. Required for Agrobacterium VirE2 nuclear import and tumorigenicity. Promotes transient expression of T-DNA in early stages by interacting with VirE2 in complex with the T-DNA and facilitating its translocation to the nucleus, and mediates stable genetic transformation by Agrobacterium by binding H2A histone. Prevents cell differentiation and shoot formation. Li [...] (341 aa)
           
  0.949
PBRP
Plant-specific TFIIB-related protein (503 aa)
           
  0.710
IMPA-1
Importin alpha isoform 1; Binds to conventional NLS motifs with high affinity in the absence of an importin beta subunit. Mediates nuclear protein import across the nuclear envelope in vitro in the absence of exogenously added importin beta subunit (PubMed-10428841). Acts as cellular receptor for the nuclear import of the virD2 protein of Agrobacterium, but is not essential for Agrobacterium-mediated root transformation (PubMed-18836040) (532 aa)
           
  0.598
VIP2
VIRE2 interacting protein 2; Transcriptional regulator required for Agrobacterium- mediated stable genetic transformation by T-DNA integration in host genome, but not for T-DNA transient expression (614 aa)
           
  0.557
CMPG1
CYS, MET, PRO, and GLY protein 1; Functions as an E3 ubiquitin ligase (431 aa)
     
   
  0.555
SKP1
S phase kinase-associated protein 1; Involved in ubiquitination and subsequent proteasomal degradation of target proteins. Together with CUL1, RBX1 and a F- box protein, it forms a SCF E3 ubiquitin ligase complex. The functional specificity of this complex depends of the type of F- box protein. In the SCF complex, it serves as an adapter that links the F-box protein to CUL1. SCF(UFO) is required for vegetative and floral organ development as well as for male gametogenesis. SCF(TIR1) is involved in auxin signaling pathway. SCF(COI1) regulates responses to jasmonates. SCF(EID1) and SCF(A [...] (160 aa)
           
  0.553
IMPA-4
Importin alpha isoform 4; Binds to conventional NLS motifs and mediates nuclear protein import across the nuclear envelope. Acts as cellular receptor for the nuclear import of the virD2 protein of Agrobacterium and is essential for Agrobacterium-mediated root transformation (538 aa)
           
  0.552
MPK3
Mitogen-activated protein kinase 3; Involved in oxidative stress-mediated signaling cascade (such as ozone). Involved in the innate immune MAP kinase signaling cascade (MEKK1, MKK4/MKK5 and MPK3/MPK6) downstream of bacterial flagellin receptor FLS2. May be involved in hypersensitive response (HR)-mediated signaling cascade by modulating LIP5 phosphorylation and subsequent multivesicular bodies (MVBs) trafficking. May phosphorylate regulators of WRKY transcription factors. Mediates the phosphorylation of VIP1 and subsequent stress genes transcription in response to Agrobacterium. MKK9-M [...] (370 aa)
     
   
  0.519
PP2-B13
Phloem protein 2-B13 (284 aa)
     
     
0.502
AT5G37490
ARM repeat superfamily protein; Functions as an E3 ubiquitin ligase (435 aa)
     
   
  0.501
Your Current Organism:
Arabidopsis thaliana
NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress
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