Groups of genes that are frequently observed in each other's genomic neighborhood.
Known metabolic pathways, protein complexes, signal transduction pathways, etc ... from curated databases.
Genes that are sometimes fused into single open reading frames.
STRING allows inspection of the interaction evidence for any given network. Choose any of the viewers above (disabled if not applicable in your network).
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
colored nodes: query proteins and first shell of interactors
white nodes: second shell of interactors
empty nodes: proteins of unknown 3D structure
filled nodes: some 3D structure is known or predicted
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
from curated databases
Uncharacterized protein (284 aa)
Predicted Functional Partners:
RHOMBOID-like 2; Rhomboid-type serine protease that catalyzes intramembrane proteolysis. Can cleave the Drosophila proteins Spitz and Keren (PubMed-16223493). May function in pollen elongation (PubMed-22007993) (317 aa)
Germin-like protein subfamily 2 member 2; May play a role in plant defense. Probably has no oxalate oxidase activity even if the active site is conserved
Laccase 11; Lignin degradation and detoxification of lignin-derived products
RHOMBOID-like 2; Rhomboid-type serine protease that catalyzes intramembrane proteolysis. Can cleave the Drosophila proteins Spitz and Keren (PubMed-16223493). May function in pollen elongation (PubMed-22007993)