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MRN1 MRN1 LUP2 LUP2 THAS1 THAS1 At5g36150 At5g36150 BAS BAS LUP1 LUP1 SQS2 SQS2 XF1 XF1 SQS1 SQS1 CAS1 CAS1 LAS1 LAS1
"XF1" - Squalene monooxygenase in Arabidopsis thaliana
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second shell of interactors
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Known Interactions
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experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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XF1Squalene monooxygenase; Catalyzes the first oxygenation step in sterol biosynthesis and is suggested to be one of the rate-limiting enzymes in this pathway. Can produce not only oxidosqualene, but also 2,3-22,23-dioxidosqualene. Main squalene epoxidase in the root. Sqe1 mutants may show defects in membrane lipid rafts, impairing the correct localization of RHD2 NADPH oxidase and the proper polarized production of ROS (531 aa)    
Predicted Functional Partners:
SQS1
Squalene synthase (410 aa)
     
 
  0.983
CAS1
Cycloartenol synthase; Converts oxidosqualene to cycloartenol and 1% parkeol. Involved in plastid biogenesis. Essential for the male gametophyte function (759 aa)
   
 
  0.978
LAS1
Lanosterol synthase 1; Converts oxidosqualene to lanosterol (756 aa)
   
 
  0.977
SQS2
Squalene synthase 2 (413 aa)
     
 
  0.976
LUP1
Lupeol synthase 1; Multifunctional enzyme that converts oxidosqualene to lupeol and 3,20-dihydroxylupane. Minor production of beta-amyrin, germanicol, taraxasterol and psi-taraxasterol (757 aa)
   
 
  0.973
LUP2
Lupeol synthase 2; Multifunctional enzyme that converts oxidosqualene to nine different triterpenes, mainly lupeol, beta-amyrin and alpha- amyrin in a 15-50-30 ratio (763 aa)
   
 
  0.972
BAS
Beta-amyrin synthase; Converts oxidosqualene to beta-amyrin (759 aa)
   
 
  0.968
THAS1
Thalianol synthase 1; Converts oxidosqualene to thalianol (766 aa)
   
 
  0.966
MRN1
Marneral synthase; Converts oxidosqualene to marneral (761 aa)
   
 
  0.966
At5g36150
Cycloartenol synthase; Converts oxidosqualene to tirucalladienol (760 aa)
   
 
  0.966
Your Current Organism:
Arabidopsis thaliana
NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress
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