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AT5G40880 AT5G40880 AT5G59140 AT5G59140 AT3G42830 AT3G42830 RUB3 RUB3 AT5G49200 AT5G49200 RBX1 RBX1 AT1G59800 AT1G59800 RCE1 RCE1 AT1G11970 AT1G11970 AT2G18600 AT2G18600 CAND1 CAND1
"AT1G59800" - Cullin family protein in Arabidopsis thaliana
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
AT1G59800Cullin family protein (255 aa)    
Predicted Functional Partners:
AT3G42830
RING-box protein 1; Component of the SCF (SKP1-CUL1-F-box protein) E3 ubiquitin ligase complex, which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. The SCF complex plays a crucial role in regulating response to auxin and is essential for growth and development. Through the RING-type zinc finger, seems to recruit the E2 ubiquitination enzyme, to the complex and brings it into close proximity to the substrate (By similarity) (115 aa)
     
  0.980
RBX1
RING-box 1 (142 aa)
       
  0.980
RUB3
NEDD8-like protein RUB3; May function as a stable post-translational protein modifier (78 aa)
       
  0.973
AT1G11970
Ubiquitin-like protein (99 aa)
       
  0.973
RCE1
RUB1 conjugating enzyme 1; Accepts the ubiquitin-like protein NEDD8/RUB1 from the ECR1-AXR1 E1 complex and catalyzes its covalent attachment to other proteins (184 aa)
       
  0.973
AT2G18600
Ubiquitin-conjugating enzyme E2 M; Accepts the ubiquitin-like protein NEDD8/RUB1 from the ECR1-AXR1 E1 complex and catalyzes its covalent attachment to other proteins (185 aa)
     
  0.962
AT5G59140
BTB/POZ domain-containing protein (96 aa)
       
  0.954
AT5G49200
Zinc finger CCCH domain-containing protein 62 (419 aa)
     
  0.953
AT5G40880
Zinc finger CCCH domain-containing protein 59 (472 aa)
     
  0.953
CAND1
Cullin-associated NEDD8-dissociated protein 1; Key assembly factor of SCF (SKP1-CUL1-F-box protein) E3 ubiquitin ligase complexes that promotes the exchange of the substrate-recognition F-box subunit in SCF complexes, thereby playing a key role in the cellular repertoire of SCF complexes. Acts as a F-box protein exchange factor (By similarity). Required for SCF(TIR1) function. Modulates SCF(TIR1) function through its interactions with the CUL1 subunit. Represses photomorphogenesis by promoting HY5 degradation in darkness (1219 aa)
     
 
  0.938
Your Current Organism:
Arabidopsis thaliana
NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress
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