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ATG3 ATG3 APG9 APG9 VPS15 VPS15 ATG6 ATG6 FAB1A FAB1A VPS34 VPS34 PTEN1 PTEN1 FAB1B FAB1B ATHATPLC1G ATHATPLC1G FAB1C FAB1C PTEN2 PTEN2
"VPS34" - Vacuolar protein sorting 34 in Arabidopsis thaliana
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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[Homology]
Score
VPS34Vacuolar protein sorting 34 (814 aa)    
Predicted Functional Partners:
VPS15
Vacuolar protein sorting 15 (1494 aa)
     
  0.999
ATG6
AUTOPHAGY 6 (517 aa)
     
  0.999
PTEN1
Calcium/lipid-binding (CaLB) phosphatase; Protein tyrosine phosphatase that exhibits also lipid phosphatase activity. Can use phosphatidylinositol substrates such as PtdIns(3,4,5)P(3) as substrate. Pollen-specific phosphatase required for pollen development (412 aa)
       
  0.987
FAB1B
FORMS APLOID AND BINUCLEATE CELLS 1B; The PI(3,5)P2 regulatory complex regulates both the synthesis and turnover of phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2). Catalyzes the phosphorylation of phosphatidylinositol 3-phosphate on the fifth hydroxyl of the myo- inositol ring, to form phosphatidylinositol 3,5-bisphosphate (By similarity). Plays an important role in maintenance of endomembrane homeostasis including endocytosis, vacuole formation, and vacuolar acidification processes. Required for development of viable pollen. Might mediate recycling of auxin transporters (1791 aa)
     
  0.981
APG9
Autophagy 9; Required for autophagy that plays an essential role in plant nutrient recycling (PubMed-12114572). Contributes to efficient autophagic flux, especially in early autophagic process prior to the fusion of the autophagosome with the vacuole (PubMed-24805779) (866 aa)
     
  0.979
FAB1A
FORMS APLOID AND BINUCLEATE CELLS 1A; The PI(3,5)P2 regulatory complex regulates both the synthesis and turnover of phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2). Catalyzes the phosphorylation of phosphatidylinositol 3-phosphate on the fifth hydroxyl of the myo- inositol ring, to form phosphatidylinositol 3,5-bisphosphate (By similarity). Plays an important role in maintenance of endomembrane homeostasis including endocytosis, vacuole formation, and vacuolar acidification processes. Required for development of viable pollen. Might mediate recycling of auxin transporters (1757 aa)
     
  0.979
ATG3
Autophagy 3 (APG3); E2 conjugating enzyme responsible for the E2-like covalent binding of phosphatidylethanolamine to the C-terminal Gly of ATG8. This step is required for the membrane association of ATG8. The formation of the ATG8-phosphatidylethanolamine conjugate is essential for autophagy and for the cytoplasm to vacuole transport (Cvt) (313 aa)
     
 
  0.977
ATHATPLC1G
Phospholipase C1; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. Required for secondary responses to abscisic acid signals (561 aa)
       
  0.975
FAB1C
FORMS APLOID AND BINUCLEATE CELLS 1C; The PI(3,5)P2 regulatory complex regulates both the synthesis and turnover of phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2). Catalyzes the phosphorylation of phosphatidylinositol 3-phosphate on the fifth hydroxyl of the myo- inositol ring, to form phosphatidylinositol 3,5-bisphosphate (By similarity) (1648 aa)
     
  0.973
PTEN2
PTEN 2; Binds phosphatidic acid. Protein tyrosine phosphatase that exhibits also lipid phosphatase activity. Hydrolyzed poorly p-nitrophenyl phosphate (p-NPP). Can use PtdIns isomers as substrates. Removes efficiently phosphate from the D3 position of the inositol ring, less from the D4 position and not at all from the D5 position on monophosphorylated PtdIns isomers (PIPs). The presence of a phosphate group in the D5 position on PIP(2) isomers reduces lipid phosphatase activity. Mostly active on PtdIns(3)P and PtdIns(3,4)P(2), to a lower extend, on PtdIns(4)P and PtdIns(3,5)P(2), but [...] (611 aa)
     
  0.973
Your Current Organism:
Arabidopsis thaliana
NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress
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