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AAE14 AAE14 DHNAT2 DHNAT2 AT3G61200 AT3G61200 AAE5 AAE5 ECHID ECHID ICS2 ICS2 PHYLLO PHYLLO AT4G05160 AT4G05160 AT5G16340 AT5G16340 AT1G04290 AT1G04290 DHNAT1 DHNAT1
"ECHID" - Naphthoate synthase in Arabidopsis thaliana
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second shell of interactors
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experimentally determined
Predicted Interactions
gene neighborhood
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gene co-occurrence
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textmining
co-expression
protein homology
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ECHIDNaphthoate synthase; Involved in the biosynthesis of phylloquinone (vitamin K1). Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2- naphthoyl-CoA (DHNA-CoA) (By similarity) (337 aa)    
Predicted Functional Partners:
AAE14
Acyl-activating enzyme 14; Involved in the biosynthesis of phylloquinone (vitamin K1). Converts 2-succinylbenzoate (OSB) to 2-succinylbenzoyl-CoA (OSB-CoA) (560 aa)
   
 
  0.993
PHYLLO
PHYLLO; Multifunctional enzyme required for phylloquinone (vitamin K1) biosynthesis (1715 aa)
   
 
  0.940
DHNAT1
DHNA-CoA thioesterase 1; Catalyzes the hydrolysis of the thioester bond of 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA) in peroxisomes, a necessary step to form the naphthoquinone ring of phylloquinone (vitamin K(1)). Is not active on benzoyl-CoA, phenylacetyl-CoA, succinyl- CoA and palmitoyl-CoA thioesters (156 aa)
 
   
  0.854
DHNAT2
DHNA-CoA thioesterase 2; Catalyzes the hydrolysis of the thioester bond of 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA) in peroxisomes, a necessary step to form the naphthoquinone ring of phylloquinone (vitamin K(1)). Displayed also slight thioesterase activity towards benzoyl-CoA. Is not active on phenylacetyl-CoA, succinyl-CoA and palmitoyl-CoA thioesters (157 aa)
 
   
  0.849
AT1G04290
Thioesterase-like protein (155 aa)
       
  0.848
AT4G05160
4-coumarate--CoA ligase-like 7; Contributes to jasmonic acid biosynthesis by initiating the beta-oxidative chain shortening of its precursors (544 aa)
   
 
  0.844
AAE5
Acyl activating enzyme 5; May act as an acid--thiol ligase that activates carboxylic acids by forming acyl-CoAs (552 aa)
   
 
  0.833
ICS2
Isochorismate synthase 2; Involved in the synthesis of salicylic acid (SA) required for both local and systemic acquired resistance (LAR and SAR) while SA synthesized through the phenylalanine ammonium lyase (PAL) pathway seems to potentiate plant cell death. Also involved in phylloquinone (vitamin K1) synthesis. Has no isochorismate pyruvate lyase (IPL) activity (562 aa)
 
     
  0.826
AT5G16340
AMP-binding protein 6; May act as an acid--thiol ligase that activates carboxylic acids by forming acyl-CoAs (550 aa)
   
 
  0.817
AT3G61200
Thioredoxin family protein (188 aa)
       
  0.810
Your Current Organism:
Arabidopsis thaliana
NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress
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