Known metabolic pathways, protein complexes, signal transduction pathways, etc ... from curated databases.
Genes that are sometimes fused into single open reading frames.
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Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
colored nodes: query proteins and first shell of interactors
white nodes: second shell of interactors
empty nodes: proteins of unknown 3D structure
filled nodes: some 3D structure is known or predicted
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
from curated databases
Encodes ATB2 (345 aa)
Predicted Functional Partners:
Class I glutamine amidotransferase-like domain-containing protein; Possesses glyoxalase I activity. Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione. May be involved in oxidative stress response (388 aa)
Ubiquitin family protein (318 aa)
Zinc finger CCCH domain-containing protein 67 (451 aa)
Ubiquitin fusion degradation UFD1-like protein (312 aa)
Uncharacterized protein (98 aa)
Basic region/leucine zipper motif 53; Transcription activator that binds DNA to the C-box-like motif (5’-TGCTGACGTCA-3’), ABRE elements, G-box-like motif (5’- CCACGTGGCC-3’), DOF (5’-AAAG-3’), I-box (5’-GATAA-3’), BS1 (5’- AGCGGG-3’), MY3 (5’-CGACG-3’), 5’-CAGTGCGC-3’ and 5’-ACTCAT-3’ sequence in target gene promoters (PubMed-15047879, PubMed-16810321, PubMed-19531597, PubMed-21278122, PubMed-25108460). DNA-binding and subsequent transcription activation is triggered by heterodimerization with other bZIP proteins (e.g. BZIP1, BZIP10 and BZIP25) (PubMed-16810321, PubMed-19531597, PubMed [...] (146 aa)
Mannose-binding lectin superfamily protein (314 aa)
Leo1-like family protein; Component of the PAF1 complex (PAF1C) which is involved in histone modifications such as methylation on histone H3 ’Lys-4’ (H3K4me3) (PubMed-20363855). Involved in regulation of flowering time. Required for the expression of the flowering repressor and MADS box gene FLC (PubMed-12207655). Involved in the control of seed dormancy and germination (PubMed-21799800) (625 aa)
NAD(P)-linked oxidoreductase-like protein (320 aa)
Membrane-anchored ubiquitin-fold protein 5; May serve as docking site to facilitate the association of other proteins to the plasma membrane (120 aa)
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NCBI taxonomy Id: 3702 Other names: A. thaliana, Arabidopsis thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress