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SAL1 SAL1 APK APK APK4 APK4 AKN2 AKN2 APS4 APS4 MET3-1 MET3-1 APS3 APS3 APS1 APS1 APR2 APR2 APK3 APK3 SIR SIR
"APR2" - 5'-adenylylsulfate reductase 2 in Arabidopsis thaliana
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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[Homology]
Score
APR25’-adenylylsulfate reductase 2; Reduces sulfate for Cys biosynthesis. Substrate preference is adenosine-5’-phosphosulfate (APS) >> 3’- phosphoadenosine-5’-phosphosulfate (PAPS). Uses glutathione or DTT as source of protons (454 aa)    
Predicted Functional Partners:
APK
APS kinase; Catalyzes the synthesis of activated sulfate. Essential for plant reproduction and viability. Required for the production of glucosinolates (276 aa)
 
  0.999
SIR
Sulfite reductase; Essential protein with sulfite reductase activity required in assimilatory sulfate reduction pathway during both primary and secondary metabolism and thus involved in development and growth (642 aa)
 
 
  0.998
AKN2
APS-kinase 2; Catalyzes the synthesis of activated sulfate. Essential for plant reproduction and viability. Required for the production of glucosinolates (293 aa)
 
  0.997
APK3
Adenylylsulfate kinase; Catalyzes the synthesis of activated sulfate. Essential for plant reproduction and viability (208 aa)
   
  0.997
APK4
Adenylylsulfate kinase; Catalyzes the synthesis of activated sulfate. Essential for plant reproduction and viability (310 aa)
 
  0.995
APS4
Sulfate adenylyltransferase (469 aa)
   
 
  0.993
APS3
ATP sulfurylase (465 aa)
   
 
  0.991
APS1
ATP sulfurylase 1; Mediates selenate (Se) reduction, and promotes Se and sulfur (S) uptake and assimilation (463 aa)
   
 
  0.991
MET3-1
Encodes a chloroplast form of ATP sulfurylase (476 aa)
   
 
  0.989
SAL1
Inositol polyphosphate 1-phosphatase; Converts adenosine 3’-phosphate 5’-phosphosulfate (PAPS) to adenosine 5’-phosphosulfate (APS) and 3’(2’)-phosphoadenosine 5’- phosphate (PAP) to AMP. May regulate the flux of sulfur in the sulfur-activation pathway by converting PAPS to APS. May play a role in the biosynthesis of sulfate conjugates and RNA processing. Is also able to hydrolyze inositol 1,4-bisphosphate and inositol 1,3,4-trisphosphate. Could be considered as a negative regulator of abscisic acid (ABA)- and stress-responsive genes, through modulating the inositol 1,4,5-trisphosphate [...] (407 aa)
   
  0.968
Your Current Organism:
Arabidopsis thaliana
NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress
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