Groups of genes that are frequently observed in each other's genomic neighborhood.
Known metabolic pathways, protein complexes, signal transduction pathways, etc ... from curated databases.
Genes that are sometimes fused into single open reading frames.
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Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
colored nodes: query proteins and first shell of interactors
white nodes: second shell of interactors
empty nodes: proteins of unknown 3D structure
filled nodes: some 3D structure is known or predicted
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
from curated databases
SLAC1 homologue 1; Slow, weak voltage-dependent S-type anion efflux channel involved in maintenance of anion homeostasis (385 aa)
Predicted Functional Partners:
Major facilitator protein; Transporter involved in a passive nitrate efflux (558 aa)
Major facilitator protein; Transporter involved in a passive nitrate efflux (548 aa)
Peptidyl-prolyl cis-trans isomerase-like 1; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides (By similarity) (164 aa)
Major facilitator protein; Transporter involved in a passive nitrate efflux (560 aa)
Tubulin alpha-2 chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain (450 aa)
Nitrate excretion transporter1; Transporter involved in a passive nitrate efflux. Not competent for chloride transport (558 aa)
Major facilitator protein; Transporter involved in a passive nitrate efflux (516 aa)
Major facilitator protein; Transporter involved in a passive nitrate efflux (555 aa)
Calcium-dependent protein kinase 21; May play a role in signal transduction pathways that involve calcium as a second messenger. Mediates the phosphorylation and activation of the S-type anion efflux channel SLAC1 (531 aa)
Potassium channel GORK; Major selective outward-rectifying potassium channel of the guard cell membrane. Involved in regulation of stomatal movements according to the water status. Assuming opened or closed conformations in response to the voltage difference across the membrane, the channel is activated by depolarization. Conductance of the channel is modulated in a potassium-dependent fashion. May interact with the cytoskeleton or with regulatory proteins (820 aa)
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NCBI taxonomy Id: 3702 Other names: A. thaliana, Arabidopsis thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress