Full Link:
STRINGSTRING
AGO9 AGO9 PWP2 PWP2 TRM82 TRM82 sks9 sks9 AT1G65370 AT1G65370 CXXS1 CXXS1 CUL4 CUL4 AT4G12100 AT4G12100 AT3G46910 AT3G46910 SUVR5 SUVR5 AT2G40780 AT2G40780
"AT1G65370" - TRAF-like family protein in Arabidopsis thaliana
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AT1G65370TRAF-like family protein (227 aa)    
Predicted Functional Partners:
CUL4
Cullin4; Component of the CUL4-RBX1-CDD (COP10-DDB1a-DET1) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Participates in the CDD complex to light-mediated control of development. May repress photomorphogenesis through enhancing COP1 E3 ubiquitin-protein ligase activity. Acts together with the CUL4- DDB1-COP1-SPA E3 ubiquitin-protein ligase complexes in the repression of photomorphogenesis and flowering time. Component ot the CUL4-RBX1-DDB1-PRL1 E3 ubiquitin-protein ligase complex which mediates ubiquitin [...] (792 aa)
     
 
  0.692
AT4G12100
Cullin family protein (434 aa)
     
 
  0.674
AT3G46910
Cullin family protein (247 aa)
     
 
  0.674
SUVR5
SU(VAR)3-9-RELATED protein 5; Histone methyltransferase that functions together with its binding partner LDL1/SWP1 as one of the regulators of flower timing in Arabidopsis (PubMed-17224141). Mediates H3K9me2 deposition and regulates gene expression in a DNA methylation- independent manner. Binds DNA through its zinc fingers and represses the expression of a subset of stimulus response genes. May represent a novel mechanism for plants to regulate their chromatin and transcriptional state, which may allow for the adaptability and modulation necessary to rapidly respond to environment or [...] (1382 aa)
       
  0.538
TRM82
tRNA modification 82; Required for the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA. In the complex, it is required to stabilize and induce conformational changes of the catalytic subunit (427 aa)
           
  0.444
AT2G40780
Nucleic acid-binding, OB-fold-like protein (171 aa)
       
      0.438
AGO9
ARGONAUTE 9; Involved in RNA-mediated post-transcriptional gene silencing (PTGS). Main component of the RNA-induced silencing complex (RISC) that binds to a short guide RNA such as a microRNA (miRNA) or small interfering RNA (siRNA). RISC uses the mature miRNA or siRNA as a guide for slicer-directed cleavage of homologous mRNAs to repress gene expression. Associates preferentially with small RNAs of 24 nucleotide in length with a 5’ terminal adenosine. Interacts with 24 nucleotide sRNAs derived from transposable elements (TEs). Required to silence pericentrometric-located TEs in female [...] (896 aa)
     
        0.435
PWP2
Periodic tryptophan protein 2 (900 aa)
           
  0.420
CXXS1
Thioredoxin-like protein CXXS1; Possesses low disulfide reductase activity, but efficient protein disulfide isomerase activity. Does not possess deglutathionylation activity (118 aa)
           
  0.420
sks9
SKU5 similar 9 (549 aa)
           
  0.420
Your Current Organism:
Arabidopsis thaliana
NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress
Server load: low (1%)