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PBG1 PBG1 EMB2107 EMB2107 RPN13 RPN13 AT4G24820 AT4G24820 RPN10 RPN10 RPN12b RPN12b ATS9 ATS9 EMB2719 EMB2719 AT1G75990 AT1G75990 UCH2 UCH2 RPN12a RPN12a
"UCH2" - Ubiquitin carboxyl-terminal hydrolase L5 in Arabidopsis thaliana
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Known Interactions
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experimentally determined
Predicted Interactions
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gene co-occurrence
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textmining
co-expression
protein homology
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UCH2Ubiquitin carboxyl-terminal hydrolase L5; Ubiquitin-protein hydrolase involved in the release of ubiquitin attached via both peptide and isopeptide linkages. Able to cleave ’Lys-48’-linked polyubiquitin chains. Involved in the direct or indirect regulation of AUX/IAA proteins stability (PubMed-17559514). Acts as a linker between the TREX-2 complex and 26S proteasome (PubMed-22951400) (330 aa)    
Predicted Functional Partners:
RPN13
Regulatory particle non-ATPase 13; Functions as a proteasomal ubiquitin receptor. Binds and presumably selects ubiquitin-conjugates for destruction. Prefers multiubiquitin chains rather than single ubiquitins, with a binding affinity for ’Lys-63’-linked ubiquitin chains (300 aa)
     
  0.998
RPN10
Regulatory particle non-ATPase 10; Plays a role in maintaining the structural integrity of the 19S regulatory particule (RP), subcomplex of the 26S proteasome. Plays a major role in both the direct and indirect recognition of ubiquitinated substrates of ubiquitin/26S proteasome-mediated proteolysis (UPP). Binds and presumably selects ubiquitin-conjugates for destruction. Prefers multiubiquitin chains rather than single ubiquitins, with a binding affinity for ’Lys-48’-linked ubiquitin chains. Acts as a potential docking subunit for both ubiquitin receptors RAD23s and DSK2s. Plays a role [...] (386 aa)
     
  0.997
PBG1
20S proteasome beta subunit G1; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity (246 aa)
     
  0.997
EMB2719
EMBRYO DEFECTIVE 2719; Acts as a regulatory subunit of the 26 proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins (488 aa)
     
  0.997
AT4G24820
26S proteasome regulatory subunit N7; Acts as a regulatory subunit of the 26S proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins (387 aa)
     
  0.997
RPN12a
Regulatory particle non-ATPase 12A; Acts as a regulatory subunit of the 26S proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins. May help to control the degradation of one or more factors that repress cytokinin signaling. Plays an important role for balancing cell expansion with cell proliferation rates during shoot development (267 aa)
     
  0.997
EMB2107
EMBRYO DEFECTIVE 2107; Acts as a regulatory subunit of the 26 proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins. Required for gametogenesis and sporophyte development. Acts redundantly with RPN5B (462 aa)
     
  0.997
AT1G75990
26S proteasome regulatory subunit N3; Acts as a regulatory subunit of the 26 proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins (487 aa)
     
  0.997
ATS9
non-ATPase subunit 9; Component of the lid subcomplex of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. In the complex, RPN6A is required for proteasome assembly (By similarity) (419 aa)
     
  0.997
RPN12b
Regulatory particle non-ATPase 12B; Acts as a regulatory subunit of the 26S proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins (233 aa)
     
  0.997
Your Current Organism:
Arabidopsis thaliana
NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress
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