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AT5G64270 AT5G64270 AT5G14130 AT5G14130 AT4G35140 AT4G35140 AMR1 AMR1 PHYLLO PHYLLO AT4G33670 AT4G33670 GLDH GLDH PANB2 PANB2 MDAR4 MDAR4 VTC5 VTC5 AT1G19550 AT1G19550
"AMR1" - Ascorbic acid mannose pathway regulator 1 in Arabidopsis thaliana
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Score
AMR1Ascorbic acid mannose pathway regulator 1 (360 aa)    
Predicted Functional Partners:
AT4G35140
WD repeat-containing protein 42A (496 aa)
           
  0.670
AT5G64270
Putative splicing factor (1269 aa)
           
  0.606
GLDH
L-galactono-1,4-lactone dehydrogenase; Involved in the biosynthesis of ascorbic acid. Required for the accumulation of respiratory complex I. Uses L-galactono- 1,4-lactone and L-gulono-1,4-lactone as substrates, but not D- galactono-1,4-lactone, D-gulono-1,4-lactone, L-mannono-1,4-lactone or D-galactonic acid. Also active with phenazine methosulfate and 1,4-benzoquinone as electron acceptors (610 aa)
           
  0.597
AT1G19550
Glutathione S-transferase-like protein (153 aa)
           
  0.596
PHYLLO
PHYLLO; Multifunctional enzyme required for phylloquinone (vitamin K1) biosynthesis (1715 aa)
           
  0.497
MDAR4
Monodehydroascorbate reductase 4; Catalyzes the conversion of monodehydroascorbate to ascorbate, oxidizing NADH in the process (PubMed-16146528). Involved in the detoxification of H(2)O(2) that escapes the peroxisome and causes oxidative damage to oil bodies (PubMed-17449810) (488 aa)
           
  0.491
VTC5
VITAMIN C DEFECTIVE 5; Catalyzes a reaction of the Smirnoff-Wheeler pathway, the major route to ascorbate biosynthesis in plants. Acts as a phosphorylase rather than as a transferase. Uses preferentially GDP-L-galactose and GDP-D-glucose as substrates. Lower activity with GDP-L-fucose, very low activity with GDP-D-mannose, and no activity with UDP-D-glucose, UDP-D-galactose or ADP-D-glucose. Highly specific for inorganic phosphate as the guanylyl acceptor (431 aa)
           
  0.491
AT5G14130
Peroxidase 55; Removal of H(2)O(2), oxidation of toxic reductants, biosynthesis and degradation of lignin, suberization, auxin catabolism, response to environmental stresses such as wounding, pathogen attack and oxidative stress. These functions might be dependent on each isozyme/isoform in each plant tissue (330 aa)
     
   
  0.461
PANB2
Phosphoenolpyruvate carboxylase family protein; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (354 aa)
           
  0.450
AT4G33670
D-threo-aldose 1-dehydrogenase; Catalyzes the oxidation of L-galactose to L-galactono- 1,4-lactone in the presence of NAD(+). Uses NAD(+) as a hydrogen acceptor much more efficiently than NADP(+) (319 aa)
           
  0.447
Your Current Organism:
Arabidopsis thaliana
NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress
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