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AT2G34210 AT2G34210 NRPD1B NRPD1B KTF1 KTF1 GTA2 GTA2 CBP20 CBP20 AT3G42660 AT3G42660 AT1G65810 AT1G65810 AT3G26560 AT3G26560 UPF3 UPF3 AT2G35920 AT2G35920 AT2G39260 AT2G39260
"AT1G65810" - DNA helicase domain-containing protein in Arabidopsis thaliana
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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AT1G65810DNA helicase domain-containing protein (1050 aa)    
Predicted Functional Partners:
AT3G26560
ATP-dependent RNA helicase, putative; May be involved in pre-mRNA splicing (1168 aa)
     
 
  0.841
AT2G35920
RNA helicase family protein (995 aa)
     
 
  0.713
AT2G39260
RNA binding protein; Recruited by UPF3 associated with the EJC core at the cytoplasmic side of the nuclear envelope and the subsequent formation of an UPF1-UPF2-UPF3 surveillance complex (including UPF1 bound to release factors at the stalled ribosome) is believed to activate NMD. In cooperation with UPF3 stimulates both ATPase and RNA helicase activities of UPF1. Binds spliced mRNA (By similarity). Involved in nonsense-mediated decay (NMD) of mRNAs containing premature stop codons by associating with the nuclear exon junction complex (EJC). Required for plant development and adaptatio [...] (1181 aa)
     
 
  0.701
AT3G42660
Chromosome transmission fidelity protein 4 (953 aa)
     
 
  0.690
NRPD1B
Nuclear RNA polymerase D1B; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Largest and catalytic component of RNA polymerase V involved in RNA-directed DNA methylation-dependent (RdDM) silencing of endogenous repeated sequences, including transposable elements. Also required for full erasure of methylation when the RNA trigger is withdrawn. Seems also involved in the synthesis of short-interfering RNAs (siRNA). Essential component of a self- reinforcing loop coupling de novo DNA methylation to siRNA pr [...] (1976 aa)
     
 
  0.687
CBP20
CAP-binding protein 20; Component of the cap-binding complex (CBC), which binds co-transcriptionally to the 5’ cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing and RNA-mediated gene silencing (RNAi) by microRNAs (miRNAs). The CBC complex is involved in miRNA-mediated RNA interference and is required for primary miRNA processing. In the CBC complex, CBP20 recognizes and binds capped RNAs (m7GpppG-capped RNA) but requires ABH1/CBP80 to stabilize the movement of its N-terminal loop and lock the CBC into a high affinity cap-binding state with the cap structur [...] (257 aa)
       
 
  0.618
KTF1
Kow domain-containing transcription factor 1; Effector of RNA-directed DNA methylation (RdDM) triggered by small interfering RNAs (siRNAs, 24-nt RNAs). Functions as an adapter protein that binds scaffold transcripts generated by polymerase V and recruits AGO4 and AGO4-bound siRNAs to form an RdDM effector complex (PubMed-19410546, PubMed-19343051). Promotes the expression of 24-nt RNAs (PubMed-19343051). Required for the initial establishment of DNA methylation (PubMed-21150311). Together with AGO4, required for transcriptional gene silencing (TGS) by DNA methylation and repressive his [...] (1493 aa)
     
 
  0.604
GTA2
Global transcription factor group A2; May regulate transcription elongation by RNA polymerase II. May enhance transcriptional pausing at sites proximal to the promoter, which may in turn facilitate the assembly of an elongation competent RNA polymerase II complex (By similarity) (1041 aa)
     
 
  0.604
AT2G34210
Transcription elongation factor Spt5; May regulate transcription elongation by RNA polymerase II. May enhance transcriptional pausing at sites proximal to the promoter, which may in turn facilitate the assembly of an elongation competent RNA polymerase II complex (By similarity) (989 aa)
     
 
  0.604
UPF3
Smg-4/UPF3-like protein; Recruits UPF2 at the cytoplasmic side of the nuclear envelope and the subsequent formation of an UPF1-UPF2-UPF3 surveillance complex (including UPF1 bound to release factors at the stalled ribosome) is believed to activate NMD. Binds spliced mRNA upstream of exon-exon junctions (By similarity). Involved in nonsense-mediated decay (NMD) of mRNAs containing premature stop codons (premature termination codon PTC) by associating with the nuclear exon junction complex (EJC) and serving as link between the EJC core and NMD machinery. Eliminates the production of nons [...] (484 aa)
       
 
  0.559
Your Current Organism:
Arabidopsis thaliana
NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress
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