Full Link:
STRINGSTRING
AT1G55750 AT1G55750 CYCT1;2 CYCT1;2 AT4G30825 AT4G30825 CYCH;1 CYCH;1 CYCT1;1 CYCT1;1 CYCT1;4 CYCT1;4 AT4G17020 AT4G17020 AT4G30820 AT4G30820 UVH6 UVH6 CAK4 CAK4 IMPA-2 IMPA-2
"CAK4" - CDK-activating kinase 4 in Arabidopsis thaliana
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CAK4CDK-activating kinase 4; Forms a stable complex with cyclin CYCH1-1 that phosphorylates human CDK2 and the C-terminal domain (CTD) of the large subunit of RNA polymerase II (348 aa)    
Predicted Functional Partners:
CYCH;1
Cyclin H;1; Associates with CDK-2 and CDK-3 and activates the CDK kinases (336 aa)
     
  0.999
AT4G30820
CDK-activating kinase assembly factor MAT1 (178 aa)
     
  0.999
UVH6
DNA repair helicase UVH6; Putative ATP-dependent 5’-3’ DNA helicase involved in nucleotide excision repair (NER) of UV-damaged DNA. May open DNA around the damage. Essential during plant growth. May negatively regulate a common response program mediated by UV damage and heat stress, that leads to tissue death and reduced chloroplast function (758 aa)
     
  0.999
AT1G55750
Transcription initiation factor TFIIH subunit H1; Component of the general transcription and DNA repair factor IIH (TFIIH) core, which is essential for both basal and activated transcription, and is involved in nucleotide excision repair (NER) of damaged DNA (591 aa)
     
  0.999
AT4G17020
Transcription factor-related; Component of the general transcription and DNA repair factor IIH (TFIIH) core, which is essential for both basal and activated transcription, and is involved in nucleotide excision repair (NER) of damaged DNA (482 aa)
     
  0.999
AT4G30825
Pentatricopeptide repeat-containing protein (904 aa)
     
  0.999
IMPA-2
Importin alpha isoform 2; Binds to conventional NLS motifs and mediates nuclear protein import across the nuclear envelope (By similarity). Acts as cellular receptor for the nuclear import of the virD2 protein of Agrobacterium, but is not essential for Agrobacterium-mediated root transformation (PubMed-18836040) (535 aa)
     
 
  0.997
CYCT1;2
Cyclin-T1-2 (460 aa)
     
  0.996
CYCT1;1
Cyclin T1-1 (247 aa)
     
  0.995
CYCT1;4
cyclin-T1-4 (541 aa)
     
  0.995
Your Current Organism:
Arabidopsis thaliana
NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress
Server load: low (2%)