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POLH POLH REV1 REV1 REV7 REV7 PCNA1 PCNA1 PCNA2 PCNA2 RPA70D RPA70D AT1G49980 AT1G49980 RPA70B RPA70B REV3 REV3 DPB2 DPB2 POLD2 POLD2
"REV3" - Recovery protein 3 in Arabidopsis thaliana
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
REV3Recovery protein 3; Catalytic subunit of the error prone DNA polymerase zeta. Involved in damage-tolerance mechanisms through translesion DNA synthesis (1916 aa)    
Predicted Functional Partners:
REV1
DNA repair protein REV1; Deoxycytidyl transferase involved in DNA repair and translesion synthesis (TLS). Transfers a dCMP residue from dCTP to the 3’-end of a DNA primer in a template-dependent reaction. Mediates also the insertion of dTMP or dGMP when the opposite base is G, and, with a low efficiency, dGMP insertions opposite G, T, and C, dAMP insertions opposite G, A, and T, and dTMP insertion opposite A. May assist in the first step in the bypass of abasic lesions by the insertion of a nucleotide opposite the lesion. Required for normal induction of mutations by physical and chemi [...] (1105 aa)
     
  0.999
REV7
Mitotic spindle assembly checkpoint protein MAD2B; Regulatory subunit of the error prone DNA polymerase zeta. Involved in damage-tolerance mechanisms through translesion DNA synthesis (By similarity) (215 aa)
       
  0.999
PCNA1
Proliferating cellular nuclear antigen 1; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase’s processibility during elongation of the leading strand (263 aa)
     
  0.997
PCNA2
Proliferating cell nuclear antigen 2; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase’s processibility during elongation of the leading strand (By similarity). May be involved in UV resistance (264 aa)
     
  0.997
AT1G49980
DNA polymerase kappa subunit (671 aa)
     
  0.995
POLH
Y-family DNA polymerase H; Error-free DNA polymerase specifically involved in DNA repair. Plays an important role in translesion synthesis (TLS), where the normal high fidelity DNA polymerases cannot proceed and DNA synthesis stalls. Plays an important role in the repair of UV- induced pyrimidine dimers and confers resistance to ultraviolet light. Depending on the context, it inserts the correct base, but may cause base transitions and transversions. Forms a Schiff base with 5’-deoxyribose phosphate at abasic sites, but does not have lyase activity. Targets POLI to replication foci. Ex [...] (672 aa)
     
 
  0.992
DPB2
DNA polymerase epsilon subunit B2; Participates in DNA repair and in chromosomal DNA replication (526 aa)
     
  0.979
POLD2
DNA polymerase delta subunit 2; The function of the small subunit is not yet clear (441 aa)
     
 
  0.975
RPA70D
Replication factor-A protein 1-related; Component of the replication protein A complex (RPA) required for DNA recombination, repair and replication. The activity of RPA is mediated by single-stranded DNA binding and protein interactions. Probably involved in repair of double-strand DNA breaks (DSBs) induced by genotoxic stresses (By similarity) (629 aa)
     
  0.974
RPA70B
RPA70-kDa subunit B; Component of the replication protein A complex (RPA) required for DNA recombination, repair and replication. The activity of RPA is mediated by single-stranded DNA binding and protein interactions (By similarity). Probably involved in repair of double-strand DNA breaks (DSBs) induced by genotoxic stresses (By similarity) (604 aa)
     
  0.974
Your Current Organism:
Arabidopsis thaliana
NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress
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