Full Link:
STRINGSTRING
VSR2 VSR2 VPS28-1 VPS28-1 VPS2.1 VPS2.1 SNX2a SNX2a VPS22 VPS22 AT3G58110 AT3G58110 ANN5 ANN5 ACT3 ACT3 AT3G28630 AT3G28630 ANX1 ANX1 ACT12 ACT12
"ANN5" - Annexin 5 in Arabidopsis thaliana
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ANN5Annexin 5 (316 aa)    
Predicted Functional Partners:
AT3G28630
Uncharacterized protein (335 aa)
     
   
  0.785
ACT3
Actin 3; Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells. Essential component of cell cytoskeleton; plays an important role in cytoplasmic streaming, cell shape determination, cell division, organelle movement and extension growth. This is considered as one of the reproductive actins (377 aa)
       
 
  0.759
VPS22
EAP30/Vps36 family protein; Component of the endosomal sorting complex required for transport II (ESCRT-II), which is required for multivesicular body (MVB) formation and sorting of endosomal cargo proteins into MVBs. The ESCRT-II complex is probably involved in the recruitment of the ESCRT-III complex (By similarity) (250 aa)
           
  0.673
VPS28-1
Vacuolar protein sorting-associated protein 28-1; Component of the ESCRT-I complex (endosomal sorting complex required for transport I), a regulator of vesicular trafficking process. Required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies (MVBs). Mediates the association to the ESCRT-0 complex (By similarity) (209 aa)
           
  0.670
VSR2
VACUOLAR SORTING RECEPTOR 2; Vacuolar-sorting receptor (VSR) involved in clathrin- coated vesicles sorting from Golgi apparatus to vacuoles (641 aa)
     
   
  0.596
SNX2a
Sorting nexin 2A; Plays a role in vesicular protein sorting (By similarity). Acts at the crossroads between the secretory and endocytic pathways. Is involved in the endosome to vacuole protein transport and, as component of the membrane-associated retromer complex, is also involved in endosome-to-Golgi retrograde transport (By similarity). Also involved in the efficient sorting of seed storage protein globulin 12S (587 aa)
           
  0.560
ANX1
ANXUR1; Receptor-like protein kinase that controls pollen tube behavior by directing rupture at proper timing to release the sperm cell (850 aa)
     
 
  0.555
VPS2.1
SNF7 family protein; Component of the ESCRT-III complex, which is required for multivesicular bodies (MVBs) formation and sorting of endosomal cargo proteins into MVBs. The ESCRT-III complex is probably involved in the concentration of MVB cargo (By similarity) (225 aa)
           
  0.554
ACT12
Actin-12; Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells. Essential component of cell cytoskeleton; plays an important role in cytoplasmic streaming, cell shape determination, cell division, organelle movement and extension growth. This is considered as one of the reproductive actins (377 aa)
     
 
  0.551
AT3G58110
Uncharacterized protein (784 aa)
       
      0.527
Your Current Organism:
Arabidopsis thaliana
NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress
Server load: low (2%)