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WPP1 WPP1 WPP3 WPP3 NTF2B NTF2B WIT2 WIT2 XI-I XI-I GIP1B GIP1B SPC98 SPC98 WPP2 WPP2 LINC1 LINC1 SUN1 SUN1 SUN2 SUN2
"WIT2" - WPP domain-interacting protein 2 in Arabidopsis thaliana
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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WIT2WPP domain-interacting protein 2; Together with WIT1, required for the nuclear envelope docking of RANGAP proteins in root tips (627 aa)    
Predicted Functional Partners:
WPP2
WPP domain protein 2; Regulates the mitotic activity in roots. Plays a role with HSP70-1 in facilitating WIT1 nuclear envelope targeting (180 aa)
       
 
  0.969
XI-I
Putative myosin; Myosin heavy chain that is required for the cell cycle- regulated transport of various organelles and proteins for their segregation. Functions by binding with its tail domain to receptor proteins on organelles and exerting force with its N-terminal motor domain against actin filaments, thereby transporting its cargo along polarized actin cables. Involved in trafficking of Golgi stacks and mitochondria (1522 aa)
       
 
  0.888
WPP3
WPP domain protein 3; Regulates the mitotic activity in roots (157 aa)
           
  0.808
SUN1
SAD1/UNC-84 domain protein 1; Component of SUN-protein-containing multivariate complexes also called LINC complexes which link the nucleoskeleton and cytoskeleton by providing versatile outer nuclear membrane attachment sites for cytoskeletal filaments (PubMed-24667841). Required for the maintenance and/or formation of polarized nuclear shape in root hairs (PubMed-21294795). Modulates the anchoring and mobility of WIP proteins and RANGAP1 in the nuclear envelope (NE) (PubMed-22270916) (471 aa)
           
  0.806
WPP1
WPP domain protein 1; Regulates the mitotic activity in roots. Plays a role with HSP70-1 in facilitating WIT1 nuclear envelope targeting (155 aa)
           
  0.804
LINC1
LITTLE NUCLEI1; Component of SUN-protein-containing multivariate complexes also called LINC complexes which link the nucleoskeleton and cytoskeleton by providing versatile outer nuclear membrane attachment sites for cytoskeletal filaments (By similarity). Required for nucleus structure organization (e.g. size and shape) (PubMed-17873096, PubMed-24308514, PubMed-23396599, PubMed-24824484) (1132 aa)
           
  0.735
GIP1B
AtGCP3 interacting protein 1; Required for gamma-tubulin complex recruitment to the centrosome (By similarity). During mitosis, modulates gamma- tubulin complex localization, spindle stability and chromosomal segregation. Necessary for gametophyte development and embryogenesis (71 aa)
           
  0.679
SUN2
SAD1/UNC-84 domain protein 2; Component of SUN-protein-containing multivariate complexes also called LINC complexes which link the nucleoskeleton and cytoskeleton by providing versatile outer nuclear membrane attachment sites for cytoskeletal filaments (PubMed-24667841). Required for the maintenance and/or formation of polarized nuclear shape in root hairs (PubMed-21294795). Modulates the anchoring and mobility of WIP proteins in the nuclear envelope (NE) (PubMed-22270916) (455 aa)
           
  0.679
NTF2B
Nuclear transport factor 2B; Facilitates protein transport into the nucleus. Could be part of a multicomponent system of cytosolic factors that assemble at the pore complex during nuclear import (By similarity) (134 aa)
           
  0.605
SPC98
Spindle pole body component 98; Gamma-tubulin complex is necessary for microtubule nucleation at the centrosome. Required for the positioning of the gamma-tubulin-containing complex on pre-existing microtubules and for the proper organization of cortical arrays (838 aa)
           
  0.603
Your Current Organism:
Arabidopsis thaliana
NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress
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