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FAH2 FAH2 ATCES1 ATCES1 SPHK2 SPHK2 TSC10B TSC10B SBH1 SBH1 T29F13.2 T29F13.2 AT5G58980 AT5G58980 TSC10A TSC10A AT2G38010 AT2G38010 AT1G07380 AT1G07380 DES-1-LIKE DES-1-LIKE
"SBH1" - Sphingoid base hydroxylase 1 in Arabidopsis thaliana
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second shell of interactors
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Known Interactions
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experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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SBH1Sphingoid base hydroxylase 1; Involved in sphingolipid trihydroxy long-chain base (4- hydroxysphinganine) biosynthesis. Can use C18- and C20-sphinganine as substrates to produce C18- and C20-phytosphinganines (D-ribo-2- amino-1,3,4-trihydroxyoctadecane and -eicosane) (260 aa)    
Predicted Functional Partners:
AT2G38010
Neutral ceramidase; Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid (792 aa)
         
  0.979
TSC10A
TSC10A; Catalyzes the reduction of 3-ketodihydrosphingosine (KDS) to dihydrosphingosine (DHS). Required for sphingolipid biosynthesis. In plants, sphingolipids seems to play a critical role in mineral ion homeostasis, most likely through their involvement in the ion transport functionalities of membrane systems in the root. Lacks stereospecificity and can also produce L-threo-DHS in addition to D-erythro-DHS (326 aa)
       
  0.972
AT5G58980
Neutral/alkaline non-lysosomal ceramidase (733 aa)
         
  0.972
AT1G07380
Neutral/alkaline non-lysosomal ceramidase (779 aa)
         
  0.972
TSC10B
TSC10B; Catalyzes the reduction of 3-ketodihydrosphingosine (KDS) to dihydrosphingosine (DHS). Required for sphingolipid biosynthesis. In plants, sphingolipids seems to play a critical role in mineral ion homeostasis, most likely through their involvement in the ion transport functionalities of membrane systems in the root. Is stereospecific for D-erythro-DHS production and does not produce L-threo-DHS (331 aa)
       
  0.970
ATCES1
Dihydroceramidase (255 aa)
       
  0.951
SPHK2
Sphingosine kinase 2; Involved in the production of sphingolipid metabolites. Phosphorylates sphingosine and various l sphingoid long-chain base (LCB) products, such as phytosphingosine (PHS, 4- hydroxysphinganine), 4-hydroxy-8-sphingenine, 4,8-sphingadienine and D-erythro-dihydrosphingosine, but has a very few activity toward D,L-threo- dihydrosphingosine. Is required for abscisic acid (ABA) signaling that mediates stomatal closure, inhibition of seed germination and root elongation. May function upstream of PLDALPHA1 and phosphatidic acid (PA) in an amplification response to ABA that [...] (481 aa)
       
  0.948
DES-1-LIKE
Sphingolipid delta-4 desaturase; Sphingolipid-delta-4-desaturase required for the biosynthesis of delta-4-unsaturated sphingolipids and derivatives. May be required for the biosynthesis of glucosylceramides (332 aa)
     
 
    0.901
FAH2
Fatty acid hydroxylase 2; Fatty acid 2-hydroxylase involved in the alpha- hydroxylation of the long-chain fatty acid (LCFA) palmitic acid. Probably involved in the resistance response to oxidative stress (237 aa)
     
 
  0.888
T29F13.2
Fatty acid hydroxylase 1; Fatty acid 2-hydroxylase involved in the alpha- hydroxylation of sphingolipid-associated very long-chain fatty acids (VLCFA). Probably involved in the resistance response to oxidative stress (237 aa)
     
 
  0.843
Your Current Organism:
Arabidopsis thaliana
NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress
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