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CID4 CID4 AT5G14460 AT5G14460 NAP57 NAP57 CID3 CID3 CBP20 CBP20 EMB25 EMB25 AT1G70220 AT1G70220 MTR4 MTR4 AT1G76630 AT1G76630 AT1G70020 AT1G70020 AT3G46960 AT3G46960
"AT1G70220" - RNA-processing, Lsm domain in Arabidopsis thaliana
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
AT1G70220RNA-processing, Lsm domain (224 aa)    
Predicted Functional Partners:
CID4
CTC-interacting domain 4 (595 aa)
       
 
  0.956
CID3
CTC-interacting domain 3 (587 aa)
       
 
  0.956
AT1G70020
Uncharacterized protein (225 aa)
           
  0.954
AT1G76630
Superkiller protein 3-like protein; Component of the SKI complex which is thought to be involved in exosome-mediated RNA decay and associates with transcriptionally active genes in a manner dependent on PAF1 complex (PAF1C) (1168 aa)
           
  0.738
AT3G46960
Antiviral helicase SKI2; Component of the SKI complex which is thought to be involved in exosome-mediated RNA decay and associates with transcriptionally active genes in a manner dependent on PAF1 complex (PAF1C) (PubMed-22511887). Involved in the regulation of potassium deprivation stress response (PubMed-21535471) (1347 aa)
           
  0.675
MTR4
RNA helicase; ATP-dependent RNA helicase that associates with the RNA exosome complex (PubMed-21682783, PubMed-25144737). Required for proper rRNA biogenesis and development. Involved in the 3’- processing of the 7S pre-RNA to the mature 5.8S rRNA and also in the removal of rRNA maturation by-products (PubMed-21682783) (988 aa)
           
  0.673
CBP20
CAP-binding protein 20; Component of the cap-binding complex (CBC), which binds co-transcriptionally to the 5’ cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing and RNA-mediated gene silencing (RNAi) by microRNAs (miRNAs). The CBC complex is involved in miRNA-mediated RNA interference and is required for primary miRNA processing. In the CBC complex, CBP20 recognizes and binds capped RNAs (m7GpppG-capped RNA) but requires ABH1/CBP80 to stabilize the movement of its N-terminal loop and lock the CBC into a high affinity cap-binding state with the cap structur [...] (257 aa)
     
      0.671
EMB25
EMBRYO DEFECTIVE 25; RNA helicase involved in group II intron splicing (PubMed-26147377). Essential protein required during embryogenesis. Involved in post-transcriptional gene silencing. Modulates the determination of cell fate. Necessary for normal plasmodesmata (PD) development and aperture regulation (1171 aa)
           
  0.635
AT5G14460
tRNA pseudouridine synthase B (540 aa)
       
      0.573
NAP57
Homologue of NAP57; Plays a central role in ribosomal RNA processing. Probable catalytic subunit of H/ACA small nucleolar ribonucleoprotein (H/ACA snoRNP) complex, which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Pseudouridine (’psi’) residues may serve to stabilize the conformation of rRNAs (By similarity) (565 aa)
       
      0.573
Your Current Organism:
Arabidopsis thaliana
NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress
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