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Si034855m Si034855m Si035313m Si035313m Si039603m Si039603m Si035304m Si035304m CTU1 CTU1 Si035223m Si035223m Si029935m Si029935m Si021984m Si021984m Si031616m Si031616m Si033280m Si033280m Si034647m Si034647m
"CTU1" - Cytoplasmic tRNA adenylyltransferase 1 in Setaria italica
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
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CTU1Cytoplasmic tRNA adenylyltransferase 1 ; Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of tRNA(Lys), tRNA(Glu) and tRNA(Gln). Directly binds tRNAs and probably acts by catalyzing adenylation of tRNAs, an intermediate required for 2-thiolation. It is unclear whether it acts as a sulfurtransferase that transfers sulfur from thiocarboxylated URM1 onto the uridine of tRNAs at wobble position (353 aa)    
Predicted Functional Partners:
Si021984m
Cytoplasmic tRNA 2-thiolation protein 2 ; Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of tRNA(Lys), tRNA(Glu) and tRNA(Gln). May act by forming a heterodimer with NCS6/CTU1 that ligates sulfur from thiocarboxylated URM1 onto the uridine of tRNAs at wobble position (462 aa)
     
  0.997
Si031616m
Ubiquitin-related modifier 1 homolog ; Acts as a sulfur carrier required for 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln). Serves as sulfur donor in tRNA 2- thiolation reaction by being thiocarboxylated (-COSH) at its C- terminus by MOCS3. The sulfur is then transferred to tRNA to form 2-thiolation of mcm(5)S(2)U. Also acts as a ubiquitin-like protein (UBL) that is covalently conjugated via an isopeptide bond to lysine residues of target proteins. The thiocarboxylated form serves as substrate for conjugation and oxidative stress s [...] (100 aa)
       
  0.770
Si034855m
Uncharacterized protein (581 aa)
   
 
  0.735
Si029935m
Uncharacterized protein (425 aa)
     
 
  0.547
Si039603m
Uncharacterized protein (497 aa)
     
 
  0.517
Si035313m
Uncharacterized protein (502 aa)
     
 
  0.517
Si035304m
Uncharacterized protein (504 aa)
     
 
  0.517
Si035223m
Uncharacterized protein (515 aa)
     
 
  0.517
Si034647m
Uncharacterized protein (638 aa)
     
 
  0.517
Si033280m
Uncharacterized protein (498 aa)
     
 
  0.517
Your Current Organism:
Setaria italica
NCBI taxonomy Id: 4555
Other names: Paniceae, S. italica, Setaria, Setaria P.Beauv., Setaria italica, Setaria italica (L.) P.Beauv., foxtail millet
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