STRINGSTRING
SCO0807 SCO0807 SCO1464 SCO1464 SCO2988 SCO2988 SCO3137 SCO3137 SCO0355 SCO0355 SCO0400 SCO0400
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SCO0807Conserved hypothetical protein SCF43.18c; SCF43.18c, unknown, len: 107 aa. Highly similar to several proteins of unknown function e.g. Escherichia coli SW:YIIL_ECOLI(EMBL:L19201) hypothetical 12.3 KD protein YiiL (104 aa), fasta scores opt: 174 z-score: 248.9 E(): 1.8e-06 31.1% identity in 106 aa overlap and Bacillus subtilis TR:O05263(EMBL:Z93938) hypothetical 12.6 KD protein YulD (104 aa), fasta scores opt: 254 z-score: 355.8 E(): 1.9e-12 43.4% identity in 106 aa overlap. (106 aa)
SCO1464Ribulose-phosphate 3-epimerase; Catalyzes the reversible epimerization of D-ribulose 5- phosphate to D-xylulose 5-phosphate; Belongs to the ribulose-phosphate 3-epimerase family. (228 aa)
SCO2988SCE50.16, galE2, UDP-glucose 4-epimerase, len: 326 aa; highly similar to SW:EXOB_AZOBR (EMBL:Z25478) Azospirillum brasilense UDP-glucose 4-epimerase (EC 5.1.3.2) ExoB, 348 aa; fasta scores: opt: 885 z-score: 970.7 E(): 0; 46.4% identity in 319 aa overlap and to SW:GALE_STRLI (EMBL:M18953) Streptomyces lividans UDP-glucose 4-epimerase (EC 5.1.3.2) GalE, 329 aa; fasta scores: opt: 793 z-score: 870.9 E(): 0;42.7% identity in 328 aa overlap. Contains Pfam match to entry PF01370 Epimerase, NAD dependent epimerase/dehydratase family. (326 aa)
SCO3137SCE66.16c, galE1, UDP-glucose 4-epimerase (EC 5.1.3.2), len: 321aa; strongly similar to many eg. SW:P13226 (GALE_STRLI) UDP-glucose 4-epimerase from Streptomyces lividans (329 aa) fasta scores; opt: 1791, z-score: 2020.5, E(): 0, 89.4% identity in 321 aa overlap. Contains Pfam match to entry PF01370 Epimerase, NAD dependent epimerase/dehydratase family. (321 aa)
SCO0355Conserved hypothetical protein SCF41.14; SCF41.14, unknown, len: 113 aa. Shares a low level of similarity with Bacillus subtilis TR:O05263 (EMBL; Z93938) hypothetical 12.6 KD protein (104 aa), fasta scores opt: 129 z-score: 179.4 E(): 0.012 31.3% identity in 96 aa overlap. (113 aa)
SCO0400SCF62.26, possible epimerase, len: 178 aa. Similar to many including: Streptomyces griseus SW:STRM_STRGR (EMBL; X62567) dTDP-4-dehydrorhamnose 3,5-epimerase (EC 5.1.3.13) (DTDP-4-keto-6-deoxyglucose 3,5-epimerase) (DTDP-l-rhamnose synthetase) (200 aa), fasta scores opt: 340 z-score:0.0 E(): 0.0 37.78% identity in 180 aa overlap and Leptospira borgpetersenii TR:Q9ZGK0 (EMBL; AF078135) RmlC (186 aa), fasta scores pt: 432 z-score: 524.9 E(): 7.2e-22 42.3% identity in 175 aa overlap. Contains a Pfam match to entry PF00908 dTDP_sugar_isom, dTDP-4-dehydrorhamnose 3,5-epimerase. (183 aa)
Your Current Organism:
Streptomyces coelicolor
NCBI taxonomy Id: 100226
Other names: S. coelicolor A3(2), Streptomyces coelicolor A3(2)
Server load: low (22%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.