(15 nodes) Positive regulation of B cell differentiation network (Cricetulus griseus)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

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textmining

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protein homology

Your Input:
	I79_001134	Serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit gamma. (289 aa)
	Il10	Interleukin-10. (178 aa)
	Inpp5d	Phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase 1. (91 aa)
	Atp11c	Phospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily. (758 aa)
	Syk	Tyrosine-protein kinase. (611 aa)
	Grtp1	PCI domain-containing protein 2. (661 aa)
	I79_011711	Signal transducer and activator of transcription 5B. (274 aa)
	I79_011712	Signal transducer and activator of transcription. (793 aa)
	Xbp1	X-box binding protein 1 isoform 1. (330 aa)
	I79_013395	Matrix metalloproteinase-14. (539 aa)
	Pcid2	PCI domain-containing protein 2. (123 aa)
	IL2	Interleukin-2; Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Belongs to the IL-2 family. (155 aa)
	I79_019038	Nck-associated protein 1-like. (1065 aa)
	CUNHXorf65	Cytokine receptor common gamma chain. (456 aa)
	Ppp2r3c	Serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit gamma. (453 aa)

Your Current Organism:

Cricetulus griseus

NCBI taxonomy Id: 10029
Other names: C. griseus, CHO cell lines, Chinese hamster, Chinese hamsters, Cricetulus aureus, Cricetulus barabensis griseus

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CUNHXorf65	I79_011711	G3I7K3	G3HLW7	Cytokine receptor common gamma chain.	Signal transducer and activator of transcription 5B.	0.464
CUNHXorf65	I79_011712	G3I7K3	G3HLW8	Cytokine receptor common gamma chain.	Signal transducer and activator of transcription.	0.464
CUNHXorf65	IL2	G3I7K3	G3HTL8	Cytokine receptor common gamma chain.	Interleukin-2; Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Belongs to the IL-2 family.	0.958
CUNHXorf65	Il10	G3I7K3	G3HB01	Cytokine receptor common gamma chain.	Interleukin-10.	0.405
CUNHXorf65	Syk	G3I7K3	G3HIA4	Cytokine receptor common gamma chain.	Tyrosine-protein kinase.	0.427
I79_011711	CUNHXorf65	G3HLW7	G3I7K3	Signal transducer and activator of transcription 5B.	Cytokine receptor common gamma chain.	0.464
I79_011711	I79_011712	G3HLW7	G3HLW8	Signal transducer and activator of transcription 5B.	Signal transducer and activator of transcription.	0.957
I79_011712	CUNHXorf65	G3HLW8	G3I7K3	Signal transducer and activator of transcription.	Cytokine receptor common gamma chain.	0.464
I79_011712	I79_011711	G3HLW8	G3HLW7	Signal transducer and activator of transcription.	Signal transducer and activator of transcription 5B.	0.957
I79_011712	IL2	G3HLW8	G3HTL8	Signal transducer and activator of transcription.	Interleukin-2; Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Belongs to the IL-2 family.	0.559
I79_011712	Il10	G3HLW8	G3HB01	Signal transducer and activator of transcription.	Interleukin-10.	0.600
I79_011712	Syk	G3HLW8	G3HIA4	Signal transducer and activator of transcription.	Tyrosine-protein kinase.	0.432
I79_019038	Inpp5d	G3I6C2	G3IJ13	Nck-associated protein 1-like.	Phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase 1.	0.538
IL2	CUNHXorf65	G3HTL8	G3I7K3	Interleukin-2; Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Belongs to the IL-2 family.	Cytokine receptor common gamma chain.	0.958
IL2	I79_011712	G3HTL8	G3HLW8	Interleukin-2; Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Belongs to the IL-2 family.	Signal transducer and activator of transcription.	0.559
IL2	Il10	G3HTL8	G3HB01	Interleukin-2; Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Belongs to the IL-2 family.	Interleukin-10.	0.947
IL2	Syk	G3HTL8	G3HIA4	Interleukin-2; Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Belongs to the IL-2 family.	Tyrosine-protein kinase.	0.459
Il10	CUNHXorf65	G3HB01	G3I7K3	Interleukin-10.	Cytokine receptor common gamma chain.	0.405
Il10	I79_011712	G3HB01	G3HLW8	Interleukin-10.	Signal transducer and activator of transcription.	0.600
Il10	IL2	G3HB01	G3HTL8	Interleukin-10.	Interleukin-2; Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Belongs to the IL-2 family.	0.947