STRINGSTRING
I79_024314 I79_024314 I79_024593 I79_024593 Capn1 Capn1 I79_025170 I79_025170 I79_025795 I79_025795 I79_026146 I79_026146 I79_026151 I79_026151 Phb2 Phb2 Wnt5a Wnt5a I79_001487 I79_001487 Tgfbr2 Tgfbr2 Csmd1 Csmd1 Src Src I79_002693 I79_002693 Lrrc1 Lrrc1 Ddr1 Ddr1 Gli3 Gli3 Stat6 Stat6 I79_015381 I79_015381 Sostdc1 Sostdc1 I79_010622 I79_010622 I79_010613 I79_010613 Wnt4 Wnt4 I79_010159 I79_010159 Robo1 Robo1 I79_001073 I79_001073 Nrg3 Nrg3 Nr3c1 Nr3c1 Tbx3 Tbx3 Pml Pml I79_008319 I79_008319 Tfap2c Tfap2c Lrp6 Lrp6 I79_007641 I79_007641 Cav1 Cav1 Tbx2 Tbx2 I79_006881 I79_006881 Ncoa3 Ncoa3 I79_006792 I79_006792 Mst1 Mst1 I79_006650 I79_006650 I79_006442 I79_006442 I79_006254 I79_006254 Med1 Med1 Igfbp5 Igfbp5 Kdm5b Kdm5b Msx2 Msx2 Gli2 Gli2 I79_003312 I79_003312 I79_017861 I79_017861 Btrc Btrc Lrp5 Lrp5 I79_019286 I79_019286 Epha2 Epha2 Tgfb1 Tgfb1 Areg Areg Vdr Vdr I79_022023 I79_022023 Bsx Bsx Ar Ar Csf1 Csf1 I79_024048 I79_024048 Ptch1 Ptch1 Fgfr2 Fgfr2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
I79_024314Paired box protein Pax-3. (301 aa)
I79_024593Uncharacterized protein. (194 aa)
Capn1Calpain-1 catalytic subunit; Belongs to the peptidase C2 family. (740 aa)
I79_025170Slit-like 2 protein. (345 aa)
I79_025795Vitamin D3 receptor. (86 aa)
I79_026146ETS translocation variant 4. (95 aa)
I79_026151ETS translocation variant 4. (69 aa)
Phb2Prohibitin-2. (396 aa)
Wnt5aProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (330 aa)
I79_001487Progesterone receptor. (741 aa)
Tgfbr2TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (592 aa)
Csmd1CUB and sushi domain-containing protein 1. (106 aa)
SrcTyrosine-protein kinase. (536 aa)
I79_002693Netrin-1. (252 aa)
Lrrc1Leucine-rich repeat-containing protein 1. (167 aa)
Ddr1Epithelial discoidin domain-containing receptor 1 isoform 1. (910 aa)
Gli3Zinc finger protein GLI3. (1582 aa)
Stat6Signal transducer and activator of transcription. (844 aa)
I79_015381Protein scribble-like. (789 aa)
Sostdc1Sclerostin domain-containing protein 1. (193 aa)
I79_010622Leucine-rich repeat-containing protein 1. (119 aa)
I79_010613Transcription factor AP-2 gamma. (236 aa)
Wnt4Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (288 aa)
I79_010159Roundabout-like 1. (1362 aa)
Robo1Roundabout-like 1. (129 aa)
I79_001073C-C motif chemokine. (72 aa)
Nrg3Pro-neuregulin-3, membrane-bound isoform. (153 aa)
Nr3c1Glucocorticoid receptor. (748 aa)
Tbx3T-box transcription factor TBX3. (709 aa)
PmlPutative transcription factor PML. (540 aa)
I79_008319Zinc finger protein 157. (381 aa)
Tfap2cTranscription factor AP-2 gamma. (463 aa)
Lrp6Low-density lipoprotein receptor-related protein 6. (565 aa)
I79_007641Low-density lipoprotein receptor-related protein 6. (543 aa)
Cav1Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (147 aa)
Tbx2T-box transcription factor TBX2. (234 aa)
I79_006881CUB and sushi domain-containing protein 2. (3527 aa)
Ncoa3Nuclear receptor coactivator 3. (1211 aa)
I79_006792DUF1518 domain-containing protein. (200 aa)
Mst1Hepatocyte growth factor-like protein. (88 aa)
I79_006650Hepatocyte growth factor-like protein. (93 aa)
I79_006442Relaxin receptor 1. (770 aa)
I79_006254Bone morphogenetic protein 4. (406 aa)
Med1Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (1581 aa)
Igfbp5Insulin-like growth factor-binding protein 5. (271 aa)
Kdm5bLysine-specific demethylase 5B. (748 aa)
Msx2Homeobox protein MSX-2. (267 aa)
Gli2Zinc finger protein GLI2. (1547 aa)
I79_003312CUB and sushi domain-containing protein 1. (3110 aa)
I79_017861Solute carrier family 12 member 2. (706 aa)
BtrcF-box/WD repeat-containing protein 1A. (488 aa)
Lrp5Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family. (1608 aa)
I79_019286Androgen receptor. (295 aa)
Epha2Ephrin type-A receptor 2. (942 aa)
Tgfb1Transforming growth factor beta-1. (237 aa)
AregAmphiregulin. (230 aa)
VdrVitamin D3 receptor. (372 aa)
I79_022023Arginase-1; Belongs to the arginase family. (281 aa)
BsxBrain-specific homeobox protein-like. (89 aa)
ArAndrogen receptor. (517 aa)
Csf1Macrophage colony-stimulating factor 1; Cytokine that plays an essential role in the regulation of survival, proliferation and differentiation of hematopoietic precursor cells, especially mononuclear phagocytes, such as macrophages and monocytes. Promotes the release of proinflammatory chemokines, and thereby plays an important role in innate immunity and in inflammatory processes. Plays an important role in the regulation of osteoclast proliferation and differentiation, the regulation of bone resorption, and is required for normal bone development. Required for normal male and female [...] (552 aa)
I79_024048Paired box protein Pax-3. (324 aa)
Ptch1Protein patched-like 1. (1114 aa)
Fgfr2Fibroblast growth factor receptor 2. (659 aa)
Your Current Organism:
Cricetulus griseus
NCBI taxonomy Id: 10029
Other names: C. griseus, CHO cell lines, Chinese hamster, Chinese hamsters, Cricetulus aureus, Cricetulus barabensis griseus
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