STRINGSTRING
I79_018993 I79_018993 Itga5 Itga5 Tgfa Tgfa I79_019149 I79_019149 I79_019425 I79_019425 Flrt1 Flrt1 Vegfb Vegfb Socs5 Socs5 I79_020269 I79_020269 I79_020316 I79_020316 Fgf7 Fgf7 Esm1 Esm1 Irak4 Irak4 I79_020968 I79_020968 I79_020969 I79_020969 I79_021125 I79_021125 Ereg Ereg Areg Areg I79_021564 I79_021564 Grem1 Grem1 Jak2 Jak2 Yes1 Yes1 Il1rn Il1rn Il1f10 Il1f10 Il36rn Il36rn I79_023268 I79_023268 Cntf Cntf I79_023998 I79_023998 Vav2 Vav2 I79_024372 I79_024372 CgPICR_019990 CgPICR_019990 Pdgfra Pdgfra Klb Klb I79_024817 I79_024817 I79_024868 I79_024868 Csf3 Csf3 Il36b Il36b I79_025371 I79_025371 Gata3 Gata3 Tlr5 Tlr5 I79_000112 I79_000112 Fam83b Fam83b Tnk2 Tnk2 I79_000852 I79_000852 Il1rap Il1rap CgPICR_012052 CgPICR_012052 Slc9a3r1 Slc9a3r1 Flrt2 Flrt2 Pdgfb Pdgfb Fgf23 Fgf23 I79_001364 I79_001364 Arf4 Arf4 Fgf17 Fgf17 I79_001734 I79_001734 Src Src Ptprj Ptprj Fgf20 Fgf20 Tlr9 Tlr9 I79_004263 I79_004263 I79_017561 I79_017561 Lyn Lyn H671_1g1070 H671_1g1070 IL1B IL1B Frs3 Frs3 Fgf21 Fgf21 Frs2 Frs2 Pdgfd Pdgfd Npm3 Npm3 Dab2ip Dab2ip Flrt3 Flrt3 Cnot9 Cnot9 I79_015109 I79_015109 I79_015062 I79_015062 I79_015061 I79_015061 I79_014973 I79_014973 Agr2 Agr2 IL2 IL2 Il21 Il21 Irak1 Irak1 Pdgfrb Pdgfrb I79_013660 I79_013660 Rnf41 Rnf41 Myd88 Myd88 I79_012764 I79_012764 Fgf16 Fgf16 Psen1 Psen1 Fyn Fyn Nrxn1 Nrxn1 App App Kl Kl Grin2b Grin2b I79_011124 I79_011124 Gdnf Gdnf Ccdc88a Ccdc88a Timm50 Timm50 Pdcl3 Pdcl3 I79_009992 I79_009992 Vegfc Vegfc Itgb3 Itgb3 Pgf Pgf Artn Artn Rnf126 Rnf126 Fgf22 Fgf22 Fgf1 Fgf1 Nptn Nptn I79_008974 I79_008974 Glmn Glmn Sdcbp Sdcbp Ecm1 Ecm1 Pik3r1 Pik3r1 I79_005331 I79_005331 Snx1 Snx1 Fer Fer Csf2 Csf2 I79_005488 I79_005488 Cdh5 Cdh5 Il1r1 Il1r1 Erap1 Erap1 Ncstn Ncstn I79_006679 I79_006679 I79_007089 I79_007089 I79_007090 I79_007090 Il10 Il10 Il6r Il6r Shc1 Shc1 Fgf3 Fgf3 Fgf4 Fgf4 Fgf19 Fgf19 I79_018586 I79_018586 Tollip Tollip
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
I79_018993Interleukin-23 receptor. (380 aa)
Itga5Integrin alpha-5; Belongs to the integrin alpha chain family. (729 aa)
TgfaProtransforming growth factor alpha. (211 aa)
I79_019149Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (132 aa)
I79_019425Apoptosis-associated speck-like protein containing a CARD. (192 aa)
Flrt1Leucine-rich repeat transmembrane protein FLRT1. (674 aa)
VegfbVascular endothelial growth factor B; Belongs to the PDGF/VEGF growth factor family. (150 aa)
Socs5Suppressor of cytokine signaling 5. (530 aa)
I79_020269EGF-containing fibulin-like extracellular matrix protein 1. (438 aa)
I79_020316Guanine nucleotide exchange factor VAV3. (604 aa)
Fgf7Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (194 aa)
Esm1Endothelial cell-specific molecule 1. (167 aa)
Irak4Interleukin-1 receptor-associated kinase 4. (462 aa)
I79_020968Fibroblast growth factor 18; Belongs to the heparin-binding growth factors family. (104 aa)
I79_020969Fibroblast growth factor 18. (85 aa)
I79_021125Epigen. (135 aa)
EregProepiregulin. (162 aa)
AregAmphiregulin. (230 aa)
I79_021564Pro-epidermal growth factor. (699 aa)
Grem1Gremlin-1. (117 aa)
Jak2Tyrosine-protein kinase. (1122 aa)
Yes1Tyrosine-protein kinase. (541 aa)
Il1rnInterleukin-1. (157 aa)
Il1f10Interleukin-1. (152 aa)
Il36rnInterleukin-1. (145 aa)
I79_023268Disintegrin and metalloproteinase domain-containing protein 17. (527 aa)
CntfCiliary neurotrophic factor. (59 aa)
I79_023998Guanine nucleotide exchange factor VAV2. (93 aa)
Vav2Guanine nucleotide exchange factor VAV2. (453 aa)
I79_024372Guanine nucleotide exchange factor VAV2. (233 aa)
CgPICR_019990Persephin. (157 aa)
PdgfraPlatelet-derived growth factor receptor alpha; Tyrosine-protein kinase that acts as a cell-surface receptor for PDGFA, PDGFB and PDGFC and plays an essential role in the regulation of embryonic development, cell proliferation, survival and chemotaxis. Depending on the context, promotes or inhibits cell proliferation and cell migration. Plays an important role in the differentiation of bone marrow-derived mesenchymal stem cells. Required for normal skeleton development. (1082 aa)
KlbBeta-klotho; Belongs to the glycosyl hydrolase 1 family. (730 aa)
I79_024817Membrane-spanning 4-domains subfamily A member 4A. (343 aa)
I79_024868Membrane-spanning 4-domains subfamily A member 12. (263 aa)
Csf3Granulocyte colony-stimulating factor. (208 aa)
Il36bInterleukin-1. (138 aa)
I79_025371Membrane-spanning 4-domains subfamily A member 15. (136 aa)
Gata3Trans-acting T-cell-specific transcription factor GATA-3. (443 aa)
Tlr5Toll-like receptor 5; Belongs to the Toll-like receptor family. (858 aa)
I79_000112Protein FAM83B. (154 aa)
Fam83bProtein FAM83B. (756 aa)
Tnk2Activated CDC42 kinase 1; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1040 aa)
I79_000852Interleukin-1 receptor accessory protein. (266 aa)
Il1rapInterleukin-1 receptor accessory protein. (360 aa)
CgPICR_012052Growth factor receptor-bound protein 2. (217 aa)
Slc9a3r1Na(+)/H(+) exchange regulatory cofactor NHE-RF; Scaffold protein that connects plasma membrane proteins with members of the ezrin/moesin/radixin family and thereby helps to link them to the actin cytoskeleton and to regulate their surface expression. (354 aa)
Flrt2Leucine-rich repeat transmembrane protein FLRT2. (660 aa)
PdgfbPlatelet-derived growth factor subunit B; Belongs to the PDGF/VEGF growth factor family. (205 aa)
Fgf23Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (251 aa)
I79_001364Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (222 aa)
Arf4ADP-ribosylation factor 4; Belongs to the small GTPase superfamily. Arf family. (180 aa)
Fgf17Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (350 aa)
I79_001734GRB2-related adapter protein. (123 aa)
SrcTyrosine-protein kinase. (536 aa)
PtprjReceptor-type tyrosine-protein phosphatase eta. (1077 aa)
Fgf20Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (212 aa)
Tlr9Toll-like receptor 9. (1239 aa)
I79_004263Ataxin-2. (904 aa)
I79_017561Tyrosine-protein kinase Lyn. (101 aa)
LynTyrosine-protein kinase. (289 aa)
H671_1g1070Fibroblast growth factor 5-like protein; Belongs to the heparin-binding growth factors family. (239 aa)
IL1BMultifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. (237 aa)
Frs3Fibroblast growth factor receptor substrate 3. (492 aa)
Fgf21Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (206 aa)
Frs2Fibroblast growth factor receptor substrate 2. (509 aa)
PdgfdPlatelet-derived growth factor D. (253 aa)
Npm3Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (337 aa)
Dab2ipDisabled-like 2-interacting protein. (1065 aa)
Flrt3Leucine-rich repeat transmembrane protein FLRT3. (649 aa)
Cnot9Cell differentiation protein RCD1-like. (299 aa)
I79_015109Interleukin-6. (174 aa)
I79_015062Phospholipid scramblase; May mediate accelerated ATP-independent bidirectional transbilayer migration of phospholipids upon binding calcium ions that results in a loss of phospholipid asymmetry in the plasma membrane. Belongs to the phospholipid scramblase family. (390 aa)
I79_015061Phospholipid scramblase; May mediate accelerated ATP-independent bidirectional transbilayer migration of phospholipids upon binding calcium ions that results in a loss of phospholipid asymmetry in the plasma membrane. Belongs to the phospholipid scramblase family. (146 aa)
I79_014973Pro-neuregulin-2, membrane-bound isoform. (386 aa)
Agr2Anterior gradient protein 2-like. (173 aa)
IL2Interleukin-2; Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Belongs to the IL-2 family. (155 aa)
Il21Interleukin-21. (67 aa)
Irak1Interleukin-1 receptor-associated kinase 1. (494 aa)
PdgfrbBeta-type platelet-derived growth factor receptor. (528 aa)
I79_013660Beta-type platelet-derived growth factor receptor. (454 aa)
Rnf41E3 ubiquitin-protein ligase NRDP1. (317 aa)
Myd88Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response. (296 aa)
I79_012764Ras GTPase-activating protein 1. (826 aa)
Fgf16Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (115 aa)
Psen1Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (467 aa)
FynProto-oncogene tyrosine-protein kinase Fyn. (232 aa)
Nrxn1Neurexin-1-alpha. (849 aa)
AppAmyloid beta A4 protein. (433 aa)
KlKlotho. (900 aa)
Grin2bGlutamate [NMDA] receptor subunit epsilon-2. (1373 aa)
I79_011124Sorting nexin-2. (386 aa)
GdnfGlial cell line-derived neurotrophic factor. (160 aa)
Ccdc88aGirdin. (1664 aa)
Timm50Mitochondrial import inner membrane translocase subunit TIM50; Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane. (325 aa)
Pdcl3Phosducin-like protein 3. (241 aa)
I79_009992Vascular endothelial growth factor D; Belongs to the PDGF/VEGF growth factor family. (259 aa)
VegfcVascular endothelial growth factor C; Belongs to the PDGF/VEGF growth factor family. (346 aa)
Itgb3Integrin beta; Belongs to the integrin beta chain family. (975 aa)
PgfPlacenta growth factor; Belongs to the PDGF/VEGF growth factor family. (154 aa)
ArtnArtemin. (224 aa)
Rnf126RING finger protein 126. (135 aa)
Fgf22Fibroblast growth factor 22; Belongs to the heparin-binding growth factors family. (70 aa)
Fgf1Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (155 aa)
NptnNeuroplastin. (219 aa)
I79_008974Basigin. (116 aa)
GlmnGlomulin. (287 aa)
SdcbpSyntenin-1. (298 aa)
Ecm1Extracellular matrix protein 1. (563 aa)
Pik3r1Phosphatidylinositol 3-kinase regulatory subunit alpha. (726 aa)
I79_005331Receptor tyrosine-protein kinase erbB-4. (480 aa)
Snx1Sorting nexin-1. (522 aa)
FerTyrosine-protein kinase; Belongs to the protein kinase superfamily. Tyr protein kinase family. Fes/fps subfamily. (822 aa)
Csf2Granulocyte-macrophage colony-stimulating factor. (95 aa)
I79_005488Progesterone-induced-blocking factor 1. (757 aa)
Cdh5Cadherin-5; Cadherins are calcium-dependent cell adhesion proteins. (763 aa)
Il1r1Interleukin-1 receptor type I. (572 aa)
Erap1Aminopeptidase. (941 aa)
NcstnNicastrin. (615 aa)
I79_006679Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (156 aa)
I79_007089Receptor tyrosine-protein kinase erbB-4. (225 aa)
I79_007090Receptor tyrosine-protein kinase erbB-4. (182 aa)
Il10Interleukin-10. (178 aa)
Il6rInterleukin-6 receptor subunit alpha. (505 aa)
Shc1SHC-transforming protein 1. (579 aa)
Fgf3Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (171 aa)
Fgf4Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (116 aa)
Fgf19Fibroblast growth factor 15; Belongs to the heparin-binding growth factors family. (115 aa)
I79_018586Phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase PTEN. (345 aa)
TollipToll-interacting protein. (274 aa)
Your Current Organism:
Cricetulus griseus
NCBI taxonomy Id: 10029
Other names: C. griseus, CHO cell lines, Chinese hamster, Chinese hamsters, Cricetulus aureus, Cricetulus barabensis griseus
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