STRINGSTRING
Foxo3 Foxo3 I79_001484 I79_001484 Acvr1b Acvr1b Itpripl2 Itpripl2 Tnfrsf1b Tnfrsf1b I79_024478 I79_024478 I79_023808 I79_023808 I79_023775 I79_023775 Tlr3 Tlr3 Krt8 Krt8 Krt18 Krt18 Itprip Itprip I79_022268 I79_022268 Dapk1 Dapk1 Jak2 Jak2 Ripk1 Ripk1 I79_022036 I79_022036 Bag3 Bag3 Rb1cc1 Rb1cc1 Lcn2 Lcn2 Tgfb1 Tgfb1 Mybphl Mybphl Daxx Daxx Il33 Il33 Pidd1 Pidd1 Kctd5 Kctd5 I79_017517 I79_017517 I79_017320 I79_017320 IL1B IL1B Gsk3a Gsk3a Tnfrsf12a Tnfrsf12a Tradd Tradd Tnf Tnf Dele1 Dele1 Bex3 Bex3 Dab2ip Dab2ip I79_015555 I79_015555 I79_015553 I79_015553 Inhba Inhba Moap1 Moap1 CgPICR_012994 CgPICR_012994 I79_014483 I79_014483 IL2 IL2 Rnf41 Rnf41 Ikzf4 Ikzf4 Bcl2l2 Bcl2l2 Fas Fas I79_001046 I79_001046 Bcl2a1 Bcl2a1 Casp8ap2 Casp8ap2 Bcl2l10 Bcl2l10 I79_000092 I79_000092 Casp8 Casp8 Bak1 Bak1 H671_3g9857 H671_3g9857 I79_013082 I79_013082 Bid Bid Fadd Fadd Cttn Cttn I79_012953 I79_012953 I79_012926 I79_012926 I79_012727 I79_012727 Zdhhc3 Zdhhc3 Casp2 Casp2 Fgfr3 Fgfr3 Stk3 Stk3 Ngf Ngf I79_010639 I79_010639 Wwox Wwox Cx3cl1 Cx3cl1 Kitlg Kitlg I79_010429 I79_010429 Skil Skil Itgav Itgav Sfrp1 Sfrp1 I79_009066 I79_009066 Pml Pml Bcl2l1 Bcl2l1 Bcl2 Bcl2 Prdx2 Prdx2 I79_008225 I79_008225 Ddx47 Ddx47 I79_007624 I79_007624 Gsk3b Gsk3b Eya2 Eya2 Smad3 Smad3 I79_006018 I79_006018 Igf1 Igf1 I79_005352 I79_005352 Bok Bok Pik3r1 Pik3r1 Siva1 Siva1 Mllt11 Mllt11 Mcl1 Mcl1 I79_004366 I79_004366 I79_004285 I79_004285 I79_003765 I79_003765 I79_003468 I79_003468 H671_5g14837 H671_5g14837 Mknk1 Mknk1 I79_001515 I79_001515
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Foxo3Forkhead box protein O3. (672 aa)
I79_00148465 kDa Yes-associated protein. (257 aa)
Acvr1bReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (373 aa)
Itpripl2Inositol 1,4,5-triphosphate receptor-interacting protein-like 2. (534 aa)
Tnfrsf1bTumor necrosis factor receptor superfamily member 1B. (477 aa)
I79_024478Death-associated protein kinase 1. (157 aa)
I79_023808Induced myeloid leukemia cell differentiation protein Mcl-1-like. (118 aa)
I79_023775Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (256 aa)
Tlr3Toll-like receptor 3. (164 aa)
Krt8Keratin, type II cytoskeletal 8; Belongs to the intermediate filament family. (488 aa)
Krt18Keratin, type I cytoskeletal 18; Belongs to the intermediate filament family. (437 aa)
ItpripInositol 1,4,5-triphosphate receptor-interacting protein. (556 aa)
I79_022268Death-associated protein kinase 1. (184 aa)
Dapk1Death-associated protein kinase 1. (667 aa)
Jak2Tyrosine-protein kinase. (1122 aa)
Ripk1Receptor-interacting serine/threonine-protein kinase 1. (655 aa)
I79_022036Peroxiredoxin-2. (108 aa)
Bag3BAG family molecular chaperone regulator 3. (571 aa)
Rb1cc1RB1-inducible coiled-coil protein 1. (1464 aa)
Lcn2Neutrophil gelatinase-associated lipocalin; Belongs to the calycin superfamily. Lipocalin family. (229 aa)
Tgfb1Transforming growth factor beta-1. (237 aa)
MybphlProteasome endopeptidase complex. (1190 aa)
DaxxDeath domain-associated protein 6. (708 aa)
Il33Interleukin-33. (217 aa)
Pidd1Leucine-rich repeat and death domain-containing protein. (915 aa)
Kctd53-phosphoinositide-dependent protein kinase 1; Belongs to the peptidase S1 family. (799 aa)
I79_017517Interferon alpha-inducible protein 27. (80 aa)
I79_017320Poly [ADP-ribose] polymerase. (513 aa)
IL1BMultifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. (237 aa)
Gsk3aGlycogen synthase kinase-3 alpha. (653 aa)
Tnfrsf12aTumor necrosis factor receptor superfamily member 12A. (124 aa)
TraddTumor necrosis factor receptor type 1-associated DEATH domain protein. (306 aa)
TnfTumor necrosis factor; Belongs to the tumor necrosis factor family. (234 aa)
Dele1Uncharacterized protein KIAA0141. (440 aa)
Bex3Protein BEX3-like protein. (114 aa)
Dab2ipDisabled-like 2-interacting protein. (1065 aa)
I79_015555Keratin, type I cytoskeletal 18; Belongs to the intermediate filament family. (255 aa)
I79_015553Keratin, type I cytoskeletal 18; Belongs to the intermediate filament family. (131 aa)
InhbaInhibin beta A chain-like protein. (424 aa)
Moap1Modulator of apoptosis 1. (353 aa)
CgPICR_012994Interferon alpha-inducible protein 27. (222 aa)
I79_014483Serine/threonine-protein kinase 3. (118 aa)
IL2Interleukin-2; Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Belongs to the IL-2 family. (155 aa)
Rnf41E3 ubiquitin-protein ligase NRDP1. (317 aa)
Ikzf4Receptor protein-tyrosine kinase. (1902 aa)
Bcl2l2Bcl-2-like protein 2. (193 aa)
FasTumor necrosis factor receptor superfamily member 6. (124 aa)
I79_001046Neurofibromin. (2164 aa)
Bcl2a1Bcl-2-related protein A1. (203 aa)
Casp8ap2CASP8-associated protein 2. (1413 aa)
Bcl2l10Bcl-2-like protein 10. (113 aa)
I79_000092Transforming growth factor beta; Belongs to the TGF-beta family. (386 aa)
Casp8Caspase-8; Belongs to the peptidase C14A family. (481 aa)
Bak1Bcl-2-likeous antagonist/killer. (209 aa)
H671_3g9857Tumor necrosis factor receptor superfamily member 6-like protein. (170 aa)
I79_013082Homeodomain-interacting protein kinase 1. (1249 aa)
BidBH3-interacting domain death agonist; Counters the protective effect of Bcl-2. (194 aa)
FaddFAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling. (208 aa)
CttnSrc substrate cortactin. (550 aa)
I79_012953Tumor necrosis factor receptor superfamily member 22. (211 aa)
I79_012926Death domain-associated protein 6. (393 aa)
I79_012727Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family. (441 aa)
Zdhhc3Palmitoyltransferase; Belongs to the DHHC palmitoyltransferase family. (330 aa)
Casp2Caspase-2; Belongs to the peptidase C14A family. (421 aa)
Fgfr3Fibroblast growth factor receptor 3. (319 aa)
Stk3Serine/threonine-protein kinase 3. (260 aa)
NgfBeta-nerve growth factor; Belongs to the NGF-beta family. (112 aa)
I79_010639WW domain-containing oxidoreductase. (138 aa)
WwoxWW domain-containing oxidoreductase. (193 aa)
Cx3cl1Fractalkine. (335 aa)
KitlgKit ligand; Ligand for the receptor-type protein-tyrosine kinase KIT. Plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, migration and function, and in melanogenesis. Belongs to the SCF family. (273 aa)
I79_010429Palmitoyltransferase; Belongs to the DHHC palmitoyltransferase family. (215 aa)
SkilSki-like protein. (677 aa)
ItgavIntegrin alpha-V; Belongs to the integrin alpha chain family. (944 aa)
Sfrp1Secreted frizzled-related protein 1. (104 aa)
I79_009066Keratin, type II cytoskeletal 8; Belongs to the intermediate filament family. (426 aa)
PmlPutative transcription factor PML. (540 aa)
Bcl2l1Bcl-2-like protein 1. (233 aa)
Bcl2Apoptosis regulator Bcl-2. (203 aa)
Prdx2Peroxiredoxin-2. (198 aa)
I79_008225CD70 antigen; Belongs to the tumor necrosis factor family. (221 aa)
Ddx47Putative ATP-dependent RNA helicase DDX47; Belongs to the DEAD box helicase family. (586 aa)
I79_007624Rho-associated protein kinase 2; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (1071 aa)
Gsk3bGlycogen synthase kinase-3 beta. (328 aa)
Eya2Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family. (550 aa)
Smad3Mothers against decapentaplegic homolog. (363 aa)
I79_006018Gamma-aminobutyric acid receptor-associated protein. (143 aa)
Igf1Insulin-like growth factor I. (75 aa)
I79_005352Sphingosine-1-phosphate phosphatase 1. (241 aa)
BokBcl-2-related ovarian killer protein. (213 aa)
Pik3r1Phosphatidylinositol 3-kinase regulatory subunit alpha. (726 aa)
Siva1Apoptosis regulatory protein Siva; Induces CD27-mediated apoptosis. Inhibits BCL2L1 isoform Bcl- x(L) anti-apoptotic activity. Inhibits activation of NF-kappa-B and promotes T-cell receptor-mediated apoptosis. (175 aa)
Mllt11Protein AF1q. (73 aa)
Mcl1Putative induced myeloid leukemia cell differentiation protein Mcl-1 like protein. (120 aa)
I79_004366Gamma-aminobutyric acid receptor-associated protein. (148 aa)
I79_004285p2X purinoceptor 7. (805 aa)
I79_003765Protein disulfide-isomerase A3. (444 aa)
I79_003468Bcl-2-like protein 11. (141 aa)
H671_5g14837Tumor necrosis factor ligand superfamily member 6-like isoform 1; Belongs to the tumor necrosis factor family. (192 aa)
Mknk1MAP kinase-interacting serine/threonine-protein kinase 1; Belongs to the protein kinase superfamily. (415 aa)
I79_001515Tumor necrosis factor receptor superfamily member 10B. (320 aa)
Your Current Organism:
Cricetulus griseus
NCBI taxonomy Id: 10029
Other names: C. griseus, CHO cell lines, Chinese hamster, Chinese hamsters, Cricetulus aureus, Cricetulus barabensis griseus
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