(19 nodes) Hemopexin-like domain superfamily network (Cricetulus griseus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	I79_002245	Proteoglycan 4. (973 aa)
	Vtn	Vitronectin. (876 aa)
	Mmp10	Stromelysin-2. (966 aa)
	Mmp12	Macrophage metalloelastase. (464 aa)
	Mmp9	Matrix metalloproteinase-9. (710 aa)
	I79_001476	Collagenase 3. (300 aa)
	I79_007509	Matrix metalloproteinase-24. (552 aa)
	I79_013395	Matrix metalloproteinase-14. (539 aa)
	Mmp19	Matrix metalloproteinase-19. (525 aa)
	I79_014551	Matrix metalloproteinase-16. (394 aa)
	Mmp11	Stromelysin-3. (361 aa)
	Mmp25	Matrix metalloproteinase-25. (413 aa)
	Mmp28	Matrix metalloproteinase-28. (263 aa)
	Mmp17	Matrix metalloproteinase-17. (213 aa)
	Hpx	Hemopexin; Binds heme and transports it to the liver for breakdown and iron recovery, after which the free hemopexin returns to the circulation. (461 aa)
	I79_025798	Vitronectin. (230 aa)
	Mmp15	Matrix metalloproteinase-15. (555 aa)
	Mmp2	72 kDa type IV collagenase. (662 aa)
	Mmp21	Matrix metalloproteinase-21. (567 aa)

Your Current Organism:

Cricetulus griseus

NCBI taxonomy Id: 10029
Other names: C. griseus, CHO cell lines, Chinese hamster, Chinese hamsters, Cricetulus aureus, Cricetulus barabensis griseus

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Hpx	I79_002245	G3INL3	G3GWW0	Hemopexin; Binds heme and transports it to the liver for breakdown and iron recovery, after which the free hemopexin returns to the circulation.	Proteoglycan 4.	0.505
Hpx	I79_025798	G3INL3	G3IP93	Hemopexin; Binds heme and transports it to the liver for breakdown and iron recovery, after which the free hemopexin returns to the circulation.	Vitronectin.	0.441
Hpx	Mmp2	G3INL3	G3H0R8	Hemopexin; Binds heme and transports it to the liver for breakdown and iron recovery, after which the free hemopexin returns to the circulation.	72 kDa type IV collagenase.	0.556
Hpx	Mmp28	G3INL3	G3I8B5	Hemopexin; Binds heme and transports it to the liver for breakdown and iron recovery, after which the free hemopexin returns to the circulation.	Matrix metalloproteinase-28.	0.446
Hpx	Vtn	G3INL3	G3GTP7	Hemopexin; Binds heme and transports it to the liver for breakdown and iron recovery, after which the free hemopexin returns to the circulation.	Vitronectin.	0.441
I79_001476	I79_013395	G3GUV2	G3HRD0	Collagenase 3.	Matrix metalloproteinase-14.	0.725
I79_001476	I79_014551	G3GUV2	G3HUE2	Collagenase 3.	Matrix metalloproteinase-16.	0.711
I79_001476	Mmp10	G3GUV2	G3GUV4	Collagenase 3.	Stromelysin-2.	0.562
I79_001476	Mmp11	G3GUV2	G3HY12	Collagenase 3.	Stromelysin-3.	0.618
I79_001476	Mmp12	G3GUV2	G3GUV3	Collagenase 3.	Macrophage metalloelastase.	0.498
I79_001476	Mmp15	G3GUV2	G3I2X0	Collagenase 3.	Matrix metalloproteinase-15.	0.468
I79_001476	Mmp17	G3GUV2	G3I2M6	Collagenase 3.	Matrix metalloproteinase-17.	0.506
I79_001476	Mmp2	G3GUV2	G3H0R8	Collagenase 3.	72 kDa type IV collagenase.	0.439
I79_001476	Mmp25	G3GUV2	G3I019	Collagenase 3.	Matrix metalloproteinase-25.	0.506
I79_001476	Mmp9	G3GUV2	G3H8V1	Collagenase 3.	Matrix metalloproteinase-9.	0.573
I79_002245	Hpx	G3GWW0	G3INL3	Proteoglycan 4.	Hemopexin; Binds heme and transports it to the liver for breakdown and iron recovery, after which the free hemopexin returns to the circulation.	0.505
I79_013395	I79_001476	G3HRD0	G3GUV2	Matrix metalloproteinase-14.	Collagenase 3.	0.725
I79_013395	I79_014551	G3HRD0	G3HUE2	Matrix metalloproteinase-14.	Matrix metalloproteinase-16.	0.479
I79_013395	Mmp10	G3HRD0	G3GUV4	Matrix metalloproteinase-14.	Stromelysin-2.	0.566
I79_013395	Mmp12	G3HRD0	G3GUV3	Matrix metalloproteinase-14.	Macrophage metalloelastase.	0.553