STRINGSTRING
Srd5a2 Srd5a2 Axl Axl Tbx3 Tbx3 Bak1 Bak1 Esr2 Esr2 Rbp4 Rbp4 Srd5a1 Srd5a1 Bax Bax Cyp19a1 Cyp19a1 Wnt5a Wnt5a Fgf10 Fgf10 Stra6 Stra6 Tp63 Tp63 Chd7 Chd7 Tyro3 Tyro3 Lhx1 Lhx1 Mertk Mertk Lrp2 Lrp2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Srd5a23-oxo-5-alpha-steroid 4-dehydrogenase (NADP(+)). (253 aa)
AxlTyrosine-protein kinase receptor UFO isoform X2. (728 aa)
Tbx3T-box transcription factor TBX3. (130 aa)
Bak1Bcl-2 homologous antagonist/killer. (209 aa)
Esr2Estrogen receptor beta. (305 aa)
Rbp4Retinol-binding protein; Retinol-binding protein that mediates retinol transport in blood plasma. (201 aa)
Srd5a13-oxo-5-alpha-steroid 4-dehydrogenase (NADP(+)). (255 aa)
BaxApoptosis regulator BAX isoform X1. (192 aa)
Cyp19a1Aromatase; Belongs to the cytochrome P450 family. (503 aa)
Wnt5aProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (380 aa)
Fgf10Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (216 aa)
Stra6Stimulated by retinoic acid gene 6 protein homolog. (671 aa)
Tp63Tumor protein 63 (p63); Acts as a sequence specific DNA binding transcriptional activator or repressor. The isoforms contain a varying set of transactivation and auto-regulating transactivation inhibiting domains thus showing an isoform specific activity. May be required in conjunction with TP73/p73 for initiation of p53/TP53 dependent apoptosis in response to genotoxic insults and the presence of activated oncogenes. (680 aa)
Chd7chromodomain-helicase-DNA-binding protein 7 isoform X1. (2916 aa)
Tyro3Tyrosine-protein kinase receptor TYRO3. (880 aa)
Lhx1LIM/homeobox protein Lhx1; Potential transcription factor. May play a role in early mesoderm formation and later in lateral mesoderm differentiation and neurogenesis (By similarity). (406 aa)
MertkTyrosine-protein kinase Mer isoform X1. (987 aa)
Lrp2Low-density lipoprotein receptor-related protein 2. (4244 aa)
Your Current Organism:
Mesocricetus auratus
NCBI taxonomy Id: 10036
Other names: Golden hamsters, M. auratus, Syrian golden hamster, Syrian golden hamsters, Syrian hamster, Syrian hamsters, golden hamster
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